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(-)-Lobeline

Also known as: Lobeline, Inflatine, Lobelin, alpha-Lobeline, L-lobeline free base, (-)-alpha-Lobeline, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethanone, Lobron, Zoolobelin

(-)-Lobeline (CAS 90-69-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H27NO2 and a molecular weight of 337.455 g/mol. Key properties include a melting point of 130-131°, a boiling point of 485.6±15.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 247.5±20.4 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
90-69-7
Jingsj CID
J-1975288-6
Molecular Formula
C22H27NO2
Molecular Weight
337.455 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point130-131°
Boiling Point485.6±15.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point247.5±20.4 °C
Exact Mass337.204193
PSA40.54000
LogP3.61
Vapor Pressure0.0±1.3 mmHg at 25°C
Refractive Index1.563

Activity & Biological Data

Additional Information[1]. Teng L, et al. Lobeline and nicotine evoke [3H]overflow from rat striatal slices preloaded with [3H]dopamine: differential inhibition of synaptosomal and vesicular [3H]dopamine uptake. J Pharmacol Exp Ther. 1997 Mar;280(3):1432-44. [2]. Miller DK, et al. Lobeline inhibits the neurochemical and behavioral effects of amphetamine. J Pharmacol Exp Ther. 2001 Mar;296(3):1023-34. [3]. Harrod SB, et al. Lobeline attenuates d-methamphetamine self-administration in rats. J Pharmacol Exp Ther. 2001 Jul;298(1):172-9.

Frequently Asked Questions

What is the CAS number of (-)-Lobeline?

The CAS number of (-)-Lobeline is 90-69-7.

What are the molecular formula and molecular weight of (-)-Lobeline?

(-)-Lobeline has molecular formula C22H27NO2 and molecular weight 337.455 g/mol.

What are the upstream and downstream products of (-)-Lobeline?

For (-)-Lobeline, Upstream Products: Lobeline hydrochloride, N-Methoxy-N-methylbenzamide, 1-phenyl-3-buten-1-ol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "(-)-Lobeline (CAS 90-69-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975288-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.