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N-Boc-cis-4-hydroxy-D-proline methyl ester

Also known as: (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate, (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate, 1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate, Boc-Cis-D-Hyp-OMe, Methyl cis-1-Boc-4-hydroxy-D-prolinate, Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate, Methyl cis-Boc-4-hydroxy-D-prolinate, 1-O-tert-butyl 2-O-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate, (2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-methyl ester, 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-

N-Boc-cis-4-hydroxy-D-proline methyl ester (CAS 114676-69-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C11H19NO5 and a molecular weight of 245.27200 g/mol. Key properties include a melting point of 80 °C, a boiling point of 335.2ºC at 760mmHg, a density of 1.216g/cm3 and a flash point of 156.6ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
114676-69-6
Jingsj CID
J-1975135-0
Molecular Formula
C11H19NO5
Molecular Weight
245.27200 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point80 °C
Boiling Point335.2ºC at 760mmHg
Density1.216g/cm3
Flash Point156.6ºC
Exact Mass245.12600
PSA76.07000
LogP0.46760
AppearancePowder | White
Vapor Pressure8.47E-06mmHg at 25°C
Refractive Index1.5

Activity & Biological Data

TargetNon-cleavable
Additional Information[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of N-Boc-cis-4-hydroxy-D-proline methyl ester?

The CAS number of N-Boc-cis-4-hydroxy-D-proline methyl ester is 114676-69-6.

What are the molecular formula and molecular weight of N-Boc-cis-4-hydroxy-D-proline methyl ester?

N-Boc-cis-4-hydroxy-D-proline methyl ester has molecular formula C11H19NO5 and molecular weight 245.27200 g/mol.

What are the upstream and downstream products of N-Boc-cis-4-hydroxy-D-proline methyl ester?

For N-Boc-cis-4-hydroxy-D-proline methyl ester, Downstream Products: (2R,4R)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate, tert-butyl (2R,4R)-2-(fluoromethyl)-4-hydroxypyrrolidine-1-carboxylate, N-Boc-4-oxo-D-proline methyl ester.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-Boc-cis-4-hydroxy-D-proline methyl ester (CAS 114676-69-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975135-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.