(±)-Rotigotine

Also known as: N-0437, racemic N-0437, 6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol, 6-(propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol, N-0924, Rotigotine, (+/-)-

(±)-Rotigotine (CAS 92206-54-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H25NOS and a molecular weight of 315.47 g/mol. Key properties include a boiling point of 470.1±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 238.1±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 92206-54-7
Jingsj CID: J-1975052-8
Molecular Formula: C₁₉H₂₅NOS
Molecular Weight: 315.47 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	470.1±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	238.1±28.7 °C
Exact Mass	315.165680
PSA	51.71000
LogP	4.96
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.611

Activity & Biological Data

Target	Ki: Dopamine receptor; 5-HT receptor[1][2]
Additional Information	[1]. Wood M, et al. Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors. Br J Pharmacol. 2015 Feb;172(4):1124-35. [2]. Scheller D, et al. The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jan;379(1):73-86. [3]. Fenu S, et al. In vivo dopamine agonist properties of rotigotine: Role of D1 and D2 receptors. Eur J Pharmacol. 2016 Oct 5;788:183-91. [4]. Radad K, et al. Neuroprotective effect of rotigotine against complex I inhibitors, MPP+ and rotenone, in primary mesencephalic cell culture. Folia Neuropathol. 2014;52(2):179-86.

Target

Ki: Dopamine receptor; 5-HT receptor[1][2]

Additional Information

[1]. Wood M, et al. Rotigotine is a potent agonist at dopamine D1 receptors as well as at dopamine D2 and D3 receptors. Br J Pharmacol. 2015 Feb;172(4):1124-35. [2]. Scheller D, et al. The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease. Naunyn Schmiedebergs Arch Pharmacol. 2009 Jan;379(1):73-86. [3]. Fenu S, et al. In vivo dopamine agonist properties of rotigotine: Role of D1 and D2 receptors. Eur J Pharmacol. 2016 Oct 5;788:183-91. [4]. Radad K, et al. Neuroprotective effect of rotigotine against complex I inhibitors, MPP+ and rotenone, in primary mesencephalic cell culture. Folia Neuropathol. 2014;52(2):179-86.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of (±)-Rotigotine?

The CAS number of (±)-Rotigotine is 92206-54-7.

What are the molecular formula and molecular weight of (±)-Rotigotine?

(±)-Rotigotine has molecular formula C19H25NOS and molecular weight 315.47 g/mol.

What are the upstream and downstream products of (±)-Rotigotine?

For (±)-Rotigotine, Upstream Products: 2-(2-Thienyl)ethyl 4-methylbenzenesulfonate, 2-Thiopheneacetic acid, 5-Methoxy-2-tetralone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "(±)-Rotigotine (CAS 92206-54-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975052-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.