Lurasidone Hydrochloride

Also known as: Lurasidone HCl, Lurasidone monohydrochloride, Latuda, SM-13496, (3aR,4S,7R,7aS)-2-(((1R,2R)-2-((4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)methyl)cyclohexyl)methyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione hydrochloride, Lurasidonhydrochlorid, Exodiene Lurasidone

Lurasidone Hydrochloride (CAS 367514-88-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C28H37ClN4O2S and a molecular weight of 529.14 g/mol. Key properties include a melting point of 198-205°C and a flash point of 9℃. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 367514-88-3
Jingsj CID: J-1974938-3
Molecular Formula: C₂₈H₃₇ClN₄O₂S
Molecular Weight: 529.14 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	198-205°C
Flash Point	9℃
PSA	84.99000
LogP	4.19660
Storage Conditions	Refrigerator

GHS Safety & Compliance

Flammable / Acute Toxicity / Health HazardSignal word: Danger

H225 — Highly flammable liquid and vapour
H301 — Toxic if swallowed
H311 — Toxic in contact with skin
H331 — Toxic if inhaled
H370 — Causes damage to organs

Activity & Biological Data

Target	IC50: 1.68 nM (dopamine D2), 0.495 nM (5-HT7), 6.75 nM (5-HT1A)[1]
Additional Information	[1]. Ishibashi T, et al. Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity. J Pharmacol Exp Ther. 2010 Jul;334(1):171-81. [2]. Sakine Atila Karaca, et al. Development of a validated high-performance liquid chromatographic method for the determination of Lurasidone in pharmaceuticals. Marmara Pharm J. 2017;21 (4): 931-937.

Target

IC50: 1.68 nM (dopamine D2), 0.495 nM (5-HT7), 6.75 nM (5-HT1A)[1]

Additional Information

[1]. Ishibashi T, et al. Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity. J Pharmacol Exp Ther. 2010 Jul;334(1):171-81. [2]. Sakine Atila Karaca, et al. Development of a validated high-performance liquid chromatographic method for the determination of Lurasidone in pharmaceuticals. Marmara Pharm J. 2017;21 (4): 931-937.

Frequently Asked Questions

What is the CAS number of Lurasidone Hydrochloride?

The CAS number of Lurasidone Hydrochloride is 367514-88-3.

What are the molecular formula and molecular weight of Lurasidone Hydrochloride?

Lurasidone Hydrochloride has molecular formula C28H37ClN4O2S and molecular weight 529.14 g/mol.

Is Lurasidone Hydrochloride hazardous?

Lurasidone Hydrochloride has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.

What are the upstream and downstream products of Lurasidone Hydrochloride?

For Lurasidone Hydrochloride, Upstream Products: NORBORNANE-2EXO,3EXO-DICARBOXYLIC ACID-ANHYDRIDE, (3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione, (1S,2S)-1,2-cyclohexanedimethanol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Lurasidone Hydrochloride (CAS 367514-88-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1974938-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.