Nisoldipine
Also known as: Methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, Isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate, 1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-methylpropyl ester, Baymycard, Syscor, Zadipina, Sular, UNII:4I8HAB65SZ
Nisoldipine (CAS 63675-72-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H24N2O6 and a molecular weight of 388.414 g/mol. Key properties include a melting point of 147-148°C, a boiling point of 505.8±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 259.7±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H312 — Harmful in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 63675-72-9
- Jingsj CID
- J-1974499-1
- Molecular Formula
- C20H24N2O6
- Molecular Weight
- 388.414 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 147-148°C |
|---|---|
| Boiling Point | 505.8±50.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 259.7±30.1 °C |
| Exact Mass | 388.163422 |
| PSA | 110.45000 |
| LogP | 4.38 |
| Vapor Pressure | 0.0±1.3 mmHg at 25°C |
| Refractive Index | 1.544 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H312 — Harmful in contact with skin
Activity & Biological Data
| Additional Information | [1]. Hamilton SF, Houle LM, Thadani U. Rapid-release and coat-core formulations of nisoldipine in treatment of hypertension, angina, and heart failure. Heart Dis. 1999 Nov-Dec;1(5):279-88. [2]. Fodor JG. Nisoldipine CC: efficacy and tolerability in hypertension and ischemic heart disease. Cardiovasc Drugs Ther. 1997 Jan;10 Suppl 3:873-9. [3]. D.J. Duncker, J.M. Hartog, P.G. Hugenholtz, et al. The effects of nisoldipine (Bay K 5552) on cardiovascular performance and regional blood flow in pentobarbital - anaesthetized pigs with or without β-adrenoceptor blockade. British Journal of Pharmacology [4]. Jan W. De Jong, Tom Huizer, Jan G.P. Tijssen. Energy conservation by nisoldipine in ischaemic heart. British Journal of Pharmacology. 1984, 83(4): 943-949 |
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Customs & Trade Information
| HS Code | 2942000000 |
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Frequently Asked Questions
What is the CAS number of Nisoldipine?
The CAS number of Nisoldipine is 63675-72-9.
What are the molecular formula and molecular weight of Nisoldipine?
Nisoldipine has molecular formula C20H24N2O6 and molecular weight 388.414 g/mol.
Is Nisoldipine hazardous?
Nisoldipine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin.
What are the upstream and downstream products of Nisoldipine?
For Nisoldipine, Upstream Products: Methyl (Z)-3-aminocrotonate, Nifedipine, Nicardipine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Nisoldipine (CAS 63675-72-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1974499-1 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.