Vardenafil

Also known as: Levitra, Vivanza, Staxyn, 2-[2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one, 2-(2-ethoxy-5-(4-ethylpiperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one, BAY 38-9456

Vardenafil (CAS 224785-90-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C23H32N6O4S and a molecular weight of 488.60 g/mol. Key properties include a melting point of 214-216ºC, a boiling point of 692.2ºC at 760mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 372.5ºC. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H302 — Harmful if swallowed and H312 — Harmful in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 224785-90-4
Jingsj CID: J-1974498-0
Molecular Formula: C₂₃H₃₂N₆O₄S
Molecular Weight: 488.60 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	214-216ºC
Boiling Point	692.2ºC at 760mmHg
Density	1.4±0.1 g/cm3
Flash Point	372.5ºC
PSA	121.28000
LogP	2.65
Vapor Pressure	5.17E-19mmHg at 25°C
Refractive Index	1.656
Storage Conditions	?20°C

GHS Safety & Compliance

Flammable / IrritantSignal word: Danger

H225 — Highly flammable liquid and vapour
H302 — Harmful if swallowed
H312 — Harmful in contact with skin
H332 — Harmful if inhaled
H319 — Causes serious eye irritation

Activity & Biological Data

Additional Information	[1]. Saenz de Tejada, I., et al., The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil. Int J Impot Res, 2001. 13(5): p. 282-90. [2]. Goldstein, I., et al., Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: a multicenter double-blind placebo-controlled fixed-dose study. Diabetes Care, 2003. 26(3): p. 777-83.

Additional Information

[1]. Saenz de Tejada, I., et al., The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil. Int J Impot Res, 2001. 13(5): p. 282-90. [2]. Goldstein, I., et al., Vardenafil, a new phosphodiesterase type 5 inhibitor, in the treatment of erectile dysfunction in men with diabetes: a multicenter double-blind placebo-controlled fixed-dose study. Diabetes Care, 2003. 26(3): p. 777-83.

Frequently Asked Questions

What is the CAS number of Vardenafil?

The CAS number of Vardenafil is 224785-90-4.

What are the molecular formula and molecular weight of Vardenafil?

Vardenafil has molecular formula C23H32N6O4S and molecular weight 488.60 g/mol.

Is Vardenafil hazardous?

Vardenafil has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H302 — Harmful if swallowed; H312 — Harmful in contact with skin.

What are the upstream and downstream products of Vardenafil?

For Vardenafil, Upstream Products: 1-Ethylpiperazine, 2-(2-Ethoxyphenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one, 4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)benzenesulfonyl chloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Vardenafil (CAS 224785-90-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1974498-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.