Desonide

Also known as: 11β,21-Dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione, 16α-Hydroxyprednisolone acetonide, Prednacinolone, Desowen, Locapred, Sterax, Tridesilon, Topifug

Desonide (CAS 638-94-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C24H32O6 and a molecular weight of 416.507 g/mol. Key properties include a melting point of 274 - 275ºC, a boiling point of 580.1±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 196.9±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 638-94-8
Jingsj CID: J-1974341-0
Molecular Formula: C₂₄H₃₂O₆
Molecular Weight: 416.507 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	274 - 275ºC
Boiling Point	580.1±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	196.9±23.6 °C
Exact Mass	416.219879
PSA	93.06000
LogP	2.62
Vapor Pressure	0.0±3.7 mmHg at 25°C
Refractive Index	1.598
Storage Conditions	Refrigerator

Activity & Biological Data

Additional Information	[1]. Kahanek, N., C. Gelbard, and A. Hebert, Desonide: a review of formulations, efficacy and safety. Expert Opin Investig Drugs, 2008. 17(7): p. 1097-104. [2]. Castanedo-Cazares, J.P., et al., Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study. Clin Cosmet Investig Dermatol, 2013. 6: p. 29-36. [3]. Parish, D. and N. Scheinfeld, Desonide foam: a review. Drugs Today (Barc), 2008. 44(1): p. 55-62.

Additional Information

[1]. Kahanek, N., C. Gelbard, and A. Hebert, Desonide: a review of formulations, efficacy and safety. Expert Opin Investig Drugs, 2008. 17(7): p. 1097-104. [2]. Castanedo-Cazares, J.P., et al., Topical niacinamide 4% and desonide 0.05% for treatment of axillary hyperpigmentation: a randomized, double-blind, placebo-controlled study. Clin Cosmet Investig Dermatol, 2013. 6: p. 29-36. [3]. Parish, D. and N. Scheinfeld, Desonide foam: a review. Drugs Today (Barc), 2008. 44(1): p. 55-62.

Customs & Trade Information

HS Code	2937210000

Frequently Asked Questions

What is the CAS number of Desonide?

The CAS number of Desonide is 638-94-8.

What are the molecular formula and molecular weight of Desonide?

Desonide has molecular formula C24H32O6 and molecular weight 416.507 g/mol.

What are the upstream and downstream products of Desonide?

For Desonide, Upstream Products: 16α-Hydroxyprednisolone; Downstream Products: Dexbudesonide, Desisobutyryl ciclesonide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Desonide (CAS 638-94-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1974341-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.