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Diflorasone

Also known as: (6α,11β,16β)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 6α,9α-Difluoro-16β-methylprednisolone, Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16β)-, (6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, Diflorasona, Diflorasonum

Diflorasone (CAS 2557-49-5) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H28F2O5 and a molecular weight of 410.452 g/mol. Key properties include a melting point of 228-239ºC, a boiling point of 569.8±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 298.4±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
2557-49-5
Jingsj CID
J-1974332-9
Molecular Formula
C22H28F2O5
Molecular Weight
410.452 g/mol
Category
Organohalogen Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point228-239ºC
Boiling Point569.8±50.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point298.4±30.1 °C
Exact Mass410.190491
PSA94.83000
LogP1.61
Vapor Pressure0.0±3.6 mmHg at 25°C
Refractive Index1.579
Storage ConditionsRefrigerator

Activity & Biological Data

Additional Information[1]. Wickrema Sinha AJ, et al. Percutaneous absorption and excretion of tritium-labeled diflorasone diacetate, a new topical corticosteroid in the rat, monkey and man. J Invest Dermatol. 1978 Dec;71(6):372-7.

Customs & Trade Information

HS Code2937229000

Frequently Asked Questions

What is the CAS number of Diflorasone?

The CAS number of Diflorasone is 2557-49-5.

What are the molecular formula and molecular weight of Diflorasone?

Diflorasone has molecular formula C22H28F2O5 and molecular weight 410.452 g/mol.

What are the upstream and downstream products of Diflorasone?

For Diflorasone, Downstream Products: Fluticasone 17β-carboxylic acid propionate, Ticabesone Propionate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Diflorasone (CAS 2557-49-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1974332-9 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.