Ciproxifan maleate
Also known as: Ciproxifan (maleate), FUB 359 maleate, FUB-359 maleate, FUB359 maleate, cyclopropyl[4-[3-(1H-imidazol-4-yl)propoxy]phenyl]methanone maleate, cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone maleate, Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt, cc-128, Ciproxifan Moleate, (Z)-but-2-enedioic acid, cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone
Ciproxifan maleate (CAS 184025-19-2) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C20H22N2O6 and a molecular weight of 386.398 g/mol. Key properties include a boiling point of 743.6ºC at 760 mmHg and a flash point of 403.5ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 184025-19-2
- Jingsj CID
- J-1973749-0
- Molecular Formula
- C20H22N2O6
- Molecular Weight
- 386.398 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 743.6ºC at 760 mmHg |
|---|---|
| Flash Point | 403.5ºC |
| Exact Mass | 386.147797 |
| PSA | 129.58000 |
| LogP | 2.72580 |
| Vapor Pressure | 3.22E-23mmHg at 25°C |
| Storage Conditions | -20℃ |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
- H317 — May cause an allergic skin reaction
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Motawaj M, Arrang JM. Ciproxifan, a histamine H?-receptor antagonist?/?inverse agonist, modulates methamphetamine-induced sensitization in mice. Eur J Neurosci. 2011 Apr;33(7):1197-204. doi: 10.1111/j.1460-9568.2011.07618.x. [2]. Bardgett ME, Davis NN, Schultheis PJ, Griffith MS. Ciproxifan, an H3 receptor antagonist, alleviates hyperactivity and cognitive deficits in the APP Tg2576 mouse model of Alzheimer's disease. Neurobiol Learn Mem. 2011 Jan;95(1):64-72. [3]. Bardgett ME, Points M, Kleier J, Blankenship M, Griffith MS. The H3 antagonist, ciproxifan, alleviates the memory impairment but enhances the motor effects of MK-801 (dizocilpine) in rats. Neuropharmacology. 2010 Nov;59(6):492-502. [4]. Day M, et al . Differential effects of ciproxifan and nicotine on impulsivity and attention measures in the 5-choice serial reaction time test. Biochem Pharmacol. 2007 Apr 15;73(8):1123-34. [5]. Pillot C, Héron A, Schwartz JC, Arrang JM. Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, modulates the effects of methamphetamine on neuropeptide mRNA expression in rat striatum. Eur J Neurosci. 2003 Jan;17(2):307-14. |
|---|
Frequently Asked Questions
What is the CAS number of Ciproxifan maleate?
The CAS number of Ciproxifan maleate is 184025-19-2.
What are the molecular formula and molecular weight of Ciproxifan maleate?
Ciproxifan maleate has molecular formula C20H22N2O6 and molecular weight 386.398 g/mol.
Is Ciproxifan maleate hazardous?
Ciproxifan maleate has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H317 — May cause an allergic skin reaction.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Ciproxifan maleate (CAS 184025-19-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1973749-0 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.