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Tetomilast

Also known as: OPC-6535, OPC 6535, 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid, 6-[2-(3,4-diethoxyphenyl)-4-thiazolyl]-2-pyridinecarboxylic acid, 2-Pyridinecarboxylic acid, 6-[2-(3,4-diethoxyphenyl)-4-thiazolyl]-, 6-(2-(3,4-diethoxyphenyl)thiazol-4-yl)picolinic acid, 6-[2-(3,4-diethoxyphenyl)thiazole-4-yl]pyridine-2-carboxylic acid

Tetomilast (CAS 145739-56-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C19H18N2O4S and a molecular weight of 369.434 g/mol. Key properties include a boiling point of 526.1±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 272.0±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
145739-56-6
Jingsj CID
J-1973734-9
Molecular Formula
C19H18N2O4S
Molecular Weight
369.434 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point526.1±50.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point272.0±30.1 °C
Exact Mass369.103485
PSA109.78000
LogP4.39
Vapor Pressure0.0±1.5 mmHg at 25°C
Refractive Index1.601

Activity & Biological Data

Additional Information[1]. Ichikawa H, Okamoto S, Kamada N, et al. Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice. Inflamm Bowel Dis. 2008;14(11):1483-1490.

Customs & Trade Information

HS Code2934100090
Summary2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Tetomilast?

The CAS number of Tetomilast is 145739-56-6.

What are the molecular formula and molecular weight of Tetomilast?

Tetomilast has molecular formula C19H18N2O4S and molecular weight 369.434 g/mol.

What are the upstream and downstream products of Tetomilast?

For Tetomilast, Upstream Products: 3,4-Diethoxybenzonitrile, 6-Acetylpyridine-2-carboxylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Tetomilast (CAS 145739-56-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1973734-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.