4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one
Also known as: LCS-1, LCS1, 4,5-Dichloro-2-(3-methylphenyl)pyridazin-3-one, 4,5-Dichloro-2-(3-methylphenyl)-3(2H)-pyridazinone, 4,5-dichloro-2-(3-methylphenyl)-2,3-dihydropyridazin-3-one, SOD1 Inhibitor, LCS-1, 4,5-Dichloro-2-m-tolyl-2H-pyridazin-3-one, pyridazinone,2-46
4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one (CAS 41931-13-9) is a compound in the Solvents category listed in the Jingsj chemical database. It has the molecular formula C11H8Cl2N2O and a molecular weight of 255.10000 g/mol. Key properties include a boiling point of 339.6ºC at 760 mmHg, a density of 1.39g/cm3 and a flash point of 159.2ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 41931-13-9
- Jingsj CID
- J-1973636-5
- Molecular Formula
- C11H8Cl2N2O
- Molecular Weight
- 255.10000 g/mol
- Category
- Solvents
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 339.6ºC at 760 mmHg |
|---|---|
| Density | 1.39g/cm3 |
| Flash Point | 159.2ºC |
| Exact Mass | 254.00100 |
| PSA | 34.89000 |
| LogP | 2.84770 |
| Appearance | white to beige |
| Refractive Index | 1.627 |
| Storage Conditions | 2-8°C |
| Additional Property | DMSO: soluble10mg/mL (clear solutikon, warmed) |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H319 — Causes serious eye irritation
Activity & Biological Data
| Target | SOD1:1.07 μM (IC50) |
|---|---|
| Additional Information | [1]. Gupta A, et al. Nanocarrier Composed of Magnetite Core Coated with Three Polymeric Shells Mediates LCS-1 Delivery for Synthetic Lethal Therapy of BLM-Defective Colorectal Cancer Cells. Biomacromolecules. 2018 Mar 12;19(3):803-815. [2]. Somwar R, et al. Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines. Proc Natl Acad Sci U S A. 2011;108(39):16375-16380. [3]. Du T, et al. Proteomic analysis identifies mechanism(s) of overcoming bortezomib resistance via targeting ubiquitin receptor Rpn13. Leukemia. 2021 Feb;35(2):550-561. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one?
The CAS number of 4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one is 41931-13-9.
What are the molecular formula and molecular weight of 4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one?
4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one has molecular formula C11H8Cl2N2O and molecular weight 255.10000 g/mol.
Is 4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one hazardous?
4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H319 — Causes serious eye irritation.
What are the upstream and downstream products of 4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one?
For 4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one, Upstream Products: m-Tolylhydrazine, 3,4-dichloro-5-hydroxy-5H-furan-2-one.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "4,5-Dichloro-2-m-tolylpyridazin-3(2H)-one (CAS 41931-13-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1973636-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.