Rotundine
Also known as: rotundine, 6H-Dibenzo[a,g]quinolizine, 5,8,13,13a-tetrahydro-2,3,9,10-tetramethoxy-, (13aS)-, ROTUNDINE 98+%, (-)-Gindarine, (13aS)-2,3,9,10-Tetramethoxy-5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizine, (S)-Tetrahydropalmitine, [13aS,(-)]-5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine, Gindarine;(13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline, L-Tetrahydropalmatine, (-)-Tetrahydropalmatine, (S)-Tetrahydropalmatine, (-)-Corydalis B, L-THP, Gindarine, Hyndarine, Caseanine, (13aS)-2,3,9,10-tetramethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine
Rotundine (CAS 483-14-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C21H25NO4 and a molecular weight of 355.427 g/mol. Key properties include a melting point of 141-143ºC, a boiling point of 482.9±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 138.7±25.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 483-14-7
- Jingsj CID
- J-1973489-5
- Molecular Formula
- C21H25NO4
- Molecular Weight
- 355.427 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 141-143ºC |
|---|---|
| Boiling Point | 482.9±45.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 138.7±25.9 °C |
| Exact Mass | 355.178345 |
| PSA | 40.16000 |
| LogP | 3.70 |
| Vapor Pressure | 0.0±1.2 mmHg at 25°C |
| Refractive Index | 1.609 |
| Storage Conditions | Refrigerator |
Activity & Biological Data
| Target | IC50: 166 nM (D1 receptor), 1.4 μM (D2 receptor), 3.3 μM (D3 receptor), 370 nM (5-HT1A)[1] |
|---|---|
| Additional Information | [1]. Wang JB, et al. l-tetrahydropalamatine: a potential new medication for the treatment of cocaine addiction. Future Med Chem. 2012 Feb;4(2):177-86. [2]. Liu YL, et al. Effects of l-tetrahydropalmatine on locomotor sensitization to oxycodone in mice. Acta Pharmacol Sin. 2005 May;26(5):533-8. |
Frequently Asked Questions
What is the CAS number of Rotundine?
The CAS number of Rotundine is 483-14-7.
What are the molecular formula and molecular weight of Rotundine?
Rotundine has molecular formula C21H25NO4 and molecular weight 355.427 g/mol.
What are the upstream and downstream products of Rotundine?
For Rotundine, Upstream Products: Formaldehyde, Veratraldehyde; Downstream Products: L-Tetrahydropalmatine hydrochloride.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Rotundine (CAS 483-14-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1973489-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.