2-Chloro-1-(1H-indol-3-yl)ethanone
Also known as: 3CAI, 2-Chloro-1-(3-indolyl)ethanone, 3-Chloroacetylindole, Ethanone, 2-chloro-1-(1H-indol-3-yl)-, Ethanone, 2-chloro-1-(3-indolyl)-, Ethanone, 2-chloro-1H-indol-1-yl-, Chloromethyl indol-3-yl ketone, 2-chloro-1-indol-3-ylethan-1-one, BB_SC-0127
2-Chloro-1-(1H-indol-3-yl)ethanone (CAS 28755-03-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C10H8ClNO and a molecular weight of 193.63000 g/mol. Key properties include a boiling point of 379.1ºC at 760 mmHg, a density of 1.337g/cm3 and a flash point of 183ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 28755-03-5
- Jingsj CID
- J-1973254-1
- Molecular Formula
- C10H8ClNO
- Molecular Weight
- 193.63000 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 379.1ºC at 760 mmHg |
|---|---|
| Density | 1.337g/cm3 |
| Flash Point | 183ºC |
| Exact Mass | 193.02900 |
| PSA | 32.86000 |
| LogP | 2.58940 |
| Vapor Pressure | 6.02E-06mmHg at 25°C |
| Refractive Index | 1.659 |
| Storage Conditions | 2-8℃ |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H319 — Causes serious eye irritation
Activity & Biological Data
| Target | Akt1 Akt2 |
|---|---|
| Additional Information | [1]. Kim DJ, et al. (3-Chloroacetyl)-indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo. Cancer Prev Res (Phila). 2011 Nov;4(11):1842-51. |
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 2-Chloro-1-(1H-indol-3-yl)ethanone?
The CAS number of 2-Chloro-1-(1H-indol-3-yl)ethanone is 28755-03-5.
What are the molecular formula and molecular weight of 2-Chloro-1-(1H-indol-3-yl)ethanone?
2-Chloro-1-(1H-indol-3-yl)ethanone has molecular formula C10H8ClNO and molecular weight 193.63000 g/mol.
Is 2-Chloro-1-(1H-indol-3-yl)ethanone hazardous?
2-Chloro-1-(1H-indol-3-yl)ethanone has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H319 — Causes serious eye irritation.
What are the upstream and downstream products of 2-Chloro-1-(1H-indol-3-yl)ethanone?
For 2-Chloro-1-(1H-indol-3-yl)ethanone, Upstream Products: Indole, Chloroacetyl chloride, N,N-diethyl-2-chloroacetamide; Downstream Products: 4-(1H-Indol-3-yl)-1,3-thiazol-2-amine, Indole-2-carboxylic acid, 3-(Cyanoacetyl)indole.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Chloro-1-(1H-indol-3-yl)ethanone (CAS 28755-03-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1973254-1 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.