Di-tert-butyl N,N-diisopropylphosphoramidite

Also known as: Di-tert-butyl diisopropylphosphoramidite, Di-tert-butoxy(diisopropylamino)phosphine, DI-T-BUTYL N,N-DIISOPROPYLPHOSPHORAMIDITE, DI-TERT-BUTYL DIISOPROPYLPHOSPHORAMIDITE, DI-TERT-BUTYL-N,N-DIISOPROPYLPHOSPHORAMIDITE, DI-TERT-BUTYL-N,N-DIISOPROPYLPHOSPHOROAMIDITE, N,N-Bis(1-methylethyl)phosphoramidous Acid Bis(1,1-dimethylethyl)ester, N,N-Bisisopropylphosphoramidous acid bis(tert-butyl) ester, MFCD00153506

Di-tert-butyl N,N-diisopropylphosphoramidite (CAS 137348-86-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C14H32NO2P and a molecular weight of 277.39 g/mol. Key properties include a melting point of 85-90ºC 0.2 mm Hg(lit.), a boiling point of 252.2±9.0 °C at 760 mmHg, a density of 0.879 and a flash point of 106.4±18.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 137348-86-8
Jingsj CID: J-1972883-7
Molecular Formula: C₁₄H₃₂NO₂P
Molecular Weight: 277.39 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	85-90ºC 0.2 mm Hg(lit.)
Boiling Point	252.2±9.0 °C at 760 mmHg
Density	0.879
Flash Point	106.4±18.7 °C
Exact Mass	277.217072
PSA	35.29000
LogP	5.72
Vapor Pressure	0.0±0.5 mmHg at 25°C
Refractive Index	1.444
Storage Conditions	−20°C
Stability	Moisture Sensitive

GHS Safety & Compliance

IrritantSignal word: Warning

H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Frequently Asked Questions

What is the CAS number of Di-tert-butyl N,N-diisopropylphosphoramidite?

The CAS number of Di-tert-butyl N,N-diisopropylphosphoramidite is 137348-86-8.

What are the molecular formula and molecular weight of Di-tert-butyl N,N-diisopropylphosphoramidite?

Di-tert-butyl N,N-diisopropylphosphoramidite has molecular formula C14H32NO2P and molecular weight 277.39 g/mol.

Is Di-tert-butyl N,N-diisopropylphosphoramidite hazardous?

Di-tert-butyl N,N-diisopropylphosphoramidite has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Di-tert-butyl N,N-diisopropylphosphoramidite?

For Di-tert-butyl N,N-diisopropylphosphoramidite, Upstream Products: Diisopropylphosphoramidous dichloride, tert-Butanol, tert-butyl tetraisopropylphosphorodiamidite.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Di-tert-butyl N,N-diisopropylphosphoramidite (CAS 137348-86-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1972883-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.