Melanotan II

Also known as: Melanotan II acetate, Melanotan II acetate salt, MT-II, MTII, Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys-NH2), Ac-[Nle4,Asp5,D-Phe7,Lys10]α-MSH-(4-10)-NH2, Melanotan (MT)-II, Bremelanotide amide, MFCD01318793

Melanotan II (CAS 121062-08-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C50H69N15O9 and a molecular weight of 1024.178 g/mol. Key property: a density of 1.4±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 121062-08-6
Jingsj CID: J-1972727-6
Molecular Formula: C₅₀H₆₉N₁₅O₉
Molecular Weight: 1024.178 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.4±0.1 g/cm3
Exact Mass	1023.540283
PSA	382.26000
LogP	-1.27
Refractive Index	1.683
Storage Conditions	−20°C
Additional Property	H2O: 5 mg/mL, soluble

Activity & Biological Data

Additional Information	[1]. Breindahl T, et al. Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet. Drug Test Anal. 2015 Feb;7(2):164-72. [2]. Giuliano F, et al. Melanotan-II: Investigation of the inducer and facilitator effects on penile erection in anaesthetized rat. Neuroscience. 2006;138(1):293-301. [3]. Ter Laak MP, et al. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003 Feb 21;462(1-3):179-83. [4]. Wessells H, et al. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000 Oct;12 Suppl 4:S74-9. [5]. De Jonghe BC, et al. Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency. Am J Physiol Endocrinol Metab. 2012 Sep 1;303(5):E644-51.

Additional Information

[1]. Breindahl T, et al. Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet. Drug Test Anal. 2015 Feb;7(2):164-72. [2]. Giuliano F, et al. Melanotan-II: Investigation of the inducer and facilitator effects on penile erection in anaesthetized rat. Neuroscience. 2006;138(1):293-301. [3]. Ter Laak MP, et al. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003 Feb 21;462(1-3):179-83. [4]. Wessells H, et al. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000 Oct;12 Suppl 4:S74-9. [5]. De Jonghe BC, et al. Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency. Am J Physiol Endocrinol Metab. 2012 Sep 1;303(5):E644-51.

Frequently Asked Questions

What is the CAS number of Melanotan II?

The CAS number of Melanotan II is 121062-08-6.

What are the molecular formula and molecular weight of Melanotan II?

Melanotan II has molecular formula C50H69N15O9 and molecular weight 1024.178 g/mol.

What are the upstream and downstream products of Melanotan II?

For Melanotan II, Upstream Products: Boc-Arg(Tos)-OH, Boc-Lys(Fmoc)-OH, N-(tert-Butoxycarbonyl)-D-phenylalanine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Melanotan II (CAS 121062-08-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1972727-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.