Pentoxyverine

Also known as: Carbetapentane, 1-Phenylcyclopentanecarboxylic acid 2-(2-diethylaminoethoxy)ethyl ester, 2-[2-(Diethylamino)ethoxy]ethyl 1-phenylcyclopentanecarboxylate, Tuclase, Sedotussin, Atussil, Urex, Pentoxiverin, Pentoxiverine

Pentoxyverine (CAS 77-23-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H31NO3 and a molecular weight of 333.465 g/mol. Key properties include a boiling point of 435.5±30.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 217.2±24.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 77-23-6
Jingsj CID: J-1972505-4
Molecular Formula: C₂₀H₃₁NO₃
Molecular Weight: 333.465 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	435.5±30.0 °C at 760 mmHg
Density	1.0±0.1 g/cm3
Flash Point	217.2±24.6 °C
Exact Mass	333.230408
PSA	38.77000
LogP	3.29
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.517

Activity & Biological Data

Target	Ki: 75 nM (sigma-1 receptor)[4]
Additional Information	[1]. Mohamed SH, et, al. Extraction-free spectrophotometric assay of the antitussive drug pentoxyverine citrate using sulfonephthalein dyes. Spectrochim Acta A Mol Biomol Spectrosc. 2019 Nov 5;222:117186. [2]. Tortella FC, et, al. Dextromethorphan and carbetapentane: centrally acting non-opioid antitussive agents with novel anticonvulsant properties. Brain Res. 1986 Sep 24;383(1-2):314-8. [3]. Calderon SN, et, al. Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands. J Med Chem. 1994 Jul 22;37(15):2285-91. [4]. Brown C, et, al. Antitussive activity of sigma-1 receptor agonists in the guinea-pig. Br J Pharmacol. 2004 Jan;141(2):233-40.

Target

Ki: 75 nM (sigma-1 receptor)[4]

Additional Information

[1]. Mohamed SH, et, al. Extraction-free spectrophotometric assay of the antitussive drug pentoxyverine citrate using sulfonephthalein dyes. Spectrochim Acta A Mol Biomol Spectrosc. 2019 Nov 5;222:117186. [2]. Tortella FC, et, al. Dextromethorphan and carbetapentane: centrally acting non-opioid antitussive agents with novel anticonvulsant properties. Brain Res. 1986 Sep 24;383(1-2):314-8. [3]. Calderon SN, et, al. Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands. J Med Chem. 1994 Jul 22;37(15):2285-91. [4]. Brown C, et, al. Antitussive activity of sigma-1 receptor agonists in the guinea-pig. Br J Pharmacol. 2004 Jan;141(2):233-40.

Customs & Trade Information

HS Code	2921300090
Summary	2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Pentoxyverine?

The CAS number of Pentoxyverine is 77-23-6.

What are the molecular formula and molecular weight of Pentoxyverine?

Pentoxyverine has molecular formula C20H31NO3 and molecular weight 333.465 g/mol.

What are the upstream and downstream products of Pentoxyverine?

For Pentoxyverine, Upstream Products: 1-Phenylcyclopentanecarbonyl chloride, 2-[2-(Diethylamino)ethoxy]ethanol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Pentoxyverine (CAS 77-23-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1972505-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.