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5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid

Also known as: 2-Methylsulfonyl-5-chloropyrimidine-4-carboxylic acid, 2-Methanesulfonyl-5-chloro-4-pyrimidinecarboxylic acid, 4-Carboxy-5-chloro-2-methylsulfonylpyrimidine, PK11007, PK11000

5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid (CAS 38275-34-2) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H5ClN2O4S and a molecular weight of 236.63300 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
38275-34-2
Jingsj CID
J-1971930-3
Molecular Formula
C6H5ClN2O4S
Molecular Weight
236.63300 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Exact Mass235.96600
PSA105.60000
LogP1.31250
Storage Conditions-20℃

Activity & Biological Data

Targetp53[1]
Additional Information[1]. Bauer MR, et al. 2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5271-80. [2]. Synnott NC, et al. Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007. Cancer Lett. 2018 Feb 1;414:99-106

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid?

The CAS number of 5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid is 38275-34-2.

What are the molecular formula and molecular weight of 5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid?

5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid has molecular formula C6H5ClN2O4S and molecular weight 236.63300 g/mol.

What are the upstream and downstream products of 5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid?

For 5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid, Upstream Products: 5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid; Downstream Products: 5-chloro-2-(methylsulfonyl)pyrimidine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "5-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid (CAS 38275-34-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1971930-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.