Pranlukast

Also known as: ONO RS-411, ONO-RS-411, N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)benzamide, 8-[4-(4-Phenylbutoxy)benzamido]-2-(tetrazol-5-yl)-4H-1-benzopyran-4-one, Benzamide, N-(4-oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl)-4-(4-phenylbutoxy)-, N-(4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl)-p-(4-phenylbutoxy)benzamide, 4-Oxo-8-(4-(4-phenylbutoxy)benzoylamino)-2-(tetrazol-5-yl)-4H-1-benzopyran, MFCD00864631

Pranlukast (CAS 103177-37-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C27H23N5O4 and a molecular weight of 481.503 g/mol. Key properties include a melting point of 236-238ºC and a density of 1.4±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 103177-37-3
Jingsj CID: J-1971658-6
Molecular Formula: C₂₇H₂₃N₅O₄
Molecular Weight: 481.503 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	236-238ºC
Density	1.4±0.1 g/cm3
Exact Mass	481.175018
PSA	123.00000
LogP	3.88
Refractive Index	1.681
Storage Conditions	Store at +4°C

Activity & Biological Data

Target	LTE4:0.63 nM (Ki) LTD4:0.99 nM (Ki) LTC4:5640 nM (Ki)
Additional Information	[1]. Obata T, et al. In vitro antagonism of ONO-1078, a newly developed anti-asthma agent, against peptide leukotrienes in isolated guinea pig tissues. Jpn J Pharmacol. 1992 Nov;60(3):227-37. [2]. Fang SH, et al. Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells. Acta Pharmacol Sin. 2012 Dec;33(12):1511-7. [3]. Ogata M, et al. Protective effects of a leukotriene inhibitor and a leukotriene antagonist on endotoxin-induced mortality in carrageenan-pretreated mice. Infect Immun. 1992 Jun;60(6):2432-7.

Target

LTE4:0.63 nM (Ki) LTD4:0.99 nM (Ki) LTC4:5640 nM (Ki)

Additional Information

[1]. Obata T, et al. In vitro antagonism of ONO-1078, a newly developed anti-asthma agent, against peptide leukotrienes in isolated guinea pig tissues. Jpn J Pharmacol. 1992 Nov;60(3):227-37. [2]. Fang SH, et al. Nuclear translocation of cysteinyl leukotriene receptor 1 is involved in oxygen-glucose deprivation-induced damage to endothelial cells. Acta Pharmacol Sin. 2012 Dec;33(12):1511-7. [3]. Ogata M, et al. Protective effects of a leukotriene inhibitor and a leukotriene antagonist on endotoxin-induced mortality in carrageenan-pretreated mice. Infect Immun. 1992 Jun;60(6):2432-7.

Frequently Asked Questions

What is the CAS number of Pranlukast?

The CAS number of Pranlukast is 103177-37-3.

What are the molecular formula and molecular weight of Pranlukast?

Pranlukast has molecular formula C27H23N5O4 and molecular weight 481.503 g/mol.

What are the upstream and downstream products of Pranlukast?

For Pranlukast, Upstream Products: 8-Amino-2-(2H-tetrazol-5-yl)-4H-chromen-4-one hydrochloride, 1-chloro-4-phenylbutane, Methylparaben.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Pranlukast (CAS 103177-37-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1971658-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.