Abiraterone acetate
Also known as: (3β)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate, 17-(3-pyridyl)-5,16-androstadien-3beta-acetate, CB 7630, Zytiga, (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate, Abiraterone acetate (USAN)
Abiraterone acetate (CAS 154229-18-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C26H33NO2 and a molecular weight of 391.546 g/mol. Key properties include a melting point of 127-130°C, a boiling point of 506.7±50.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 260.2±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H360 — May damage fertility or the unborn child and H372 — Causes damage to organs through prolonged exposure. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 154229-18-2
- Jingsj CID
- J-1971634-8
- Molecular Formula
- C26H33NO2
- Molecular Weight
- 391.546 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 127-130°C |
|---|---|
| Boiling Point | 506.7±50.0 °C at 760 mmHg |
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 260.2±30.1 °C |
| Exact Mass | 391.251129 |
| PSA | 39.19000 |
| LogP | 6.55 |
| Vapor Pressure | 0.0±1.3 mmHg at 25°C |
| Refractive Index | 1.584 |
| Storage Conditions | -20°C Freezer |
GHS Safety & Compliance
- H360 — May damage fertility or the unborn child
- H372 — Causes damage to organs through prolonged exposure
Activity & Biological Data
| Target | CYP17[1] |
|---|---|
| Additional Information | [1]. Stein MN, et al. Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer. Asian J Androl. 2014 May-Jun;16(3):387-400. [2]. Richards J, et al. Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100. Cancer Res. 2012 May 1;72(9):2176-82. [3]. Li R, et al. Abiraterone inhibits 3β-hydroxysteroid dehydrogenase: a rationale for increasing drug exposure in castration-resistant prostate cancer. Clin Cancer Res. 2012 Jul 1;18(13):3571-9. [4]. Lee GT, et al. Intracrine androgen biosynthesis in renal cell carcinoma. Br J Cancer. 2017 Mar 28;116(7):937-943. |
Customs & Trade Information
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Abiraterone acetate?
The CAS number of Abiraterone acetate is 154229-18-2.
What are the molecular formula and molecular weight of Abiraterone acetate?
Abiraterone acetate has molecular formula C26H33NO2 and molecular weight 391.546 g/mol.
Is Abiraterone acetate hazardous?
Abiraterone acetate has GHS signal word Danger and hazard statements H360 — May damage fertility or the unborn child; H372 — Causes damage to organs through prolonged exposure.
What are the upstream and downstream products of Abiraterone acetate?
For Abiraterone acetate, Upstream Products: (3β)-Androsta-5,16-diene-3,17-diol 3-acetate 17-(trifluoromethanesulfonate), 3-Pyridineboronic acid, Abiraterone; Downstream Products: Abiraterone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Abiraterone acetate (CAS 154229-18-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1971634-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.