Tosyl-L-arginine methyl ester

Also known as: Nα-(p-Tolylsulfonyl)-L-arginine methyl ester, Nα-Tosyl-L-arginine methyl ester, TAME, Methyl N-[(4-methylphenyl)sulfonyl]argininate, (S)-methyl 5-guanidino-2-(4-methylphenylsulfonamido)pentanoate, Ts-Arg-OMe, Nα-(4-Methylphenylsulfonyl)-L-arginine methyl ester, Tosylarginine methyl ester

Tosyl-L-arginine methyl ester (CAS 901-47-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C14H22N4O4S and a molecular weight of 342.42 g/mol. Key properties include a boiling point of 516.5±60.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 266.1±32.9 °C. It is listed by 1 supplier, from 10.24 to 10.60 CNY. Record last updated Aug 21, 2026.

CAS No.: 901-47-3
Jingsj CID: J-1971297-6
Molecular Formula: C₁₄H₂₂N₄O₄S
Molecular Weight: 342.42 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Supplier	Purity / Pack	Base Price	Unit Price	Origin
Maikuo Made to Order	99% 500mg	¥5,120.00	$1.53 /mgBest ¥10.24/mg CNY	CN China MOQ 500mg	View Product
Maikuo Made to Order	99% 100mg	¥1,050.00	$1.57 /mg ¥10.50/mg CNY	CN China MOQ 100mg	View Product
Maikuo Made to Order	99% 50mg	¥530.00	$1.59 /mg ¥10.60/mg CNY	CN China MOQ 50mg	View Product

Physicochemical Properties

Boiling Point	516.5±60.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	266.1±32.9 °C
Exact Mass	342.136169
PSA	142.75000
LogP	0.77
Vapor Pressure	0.0±1.3 mmHg at 25°C
Refractive Index	1.591
Storage Conditions	-20℃
SMILES	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CCCN=C(N)N)C(=O)OC
InChIKey	FKMJXALNHKIDOD-LBPRGKRZSA-N
InChI	1S/C14H22N4O4S/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17)/t12-/m0/s1

Activity & Biological Data

Target	APC
Additional Information	[1]. Zeng X, et al. Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer Cell. 2010 Oct 19;18(4):382-95. [2]. Zeng X, et al. An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination. Nat Chem Biol. 2012 Feb 26;8(4):383-92. [3]. Ma Y, et al. Differential effects of Mg(ii) and N(alpha)-4-tosyl-l-arginine methyl ester hydrochloride on the recognition and catalysis in ATP hydrolysis. Dalton Trans. 2008 Feb 28;(8):1081-6.

Target

APC

Additional Information

[1]. Zeng X, et al. Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer Cell. 2010 Oct 19;18(4):382-95. [2]. Zeng X, et al. An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination. Nat Chem Biol. 2012 Feb 26;8(4):383-92. [3]. Ma Y, et al. Differential effects of Mg(ii) and N(alpha)-4-tosyl-l-arginine methyl ester hydrochloride on the recognition and catalysis in ATP hydrolysis. Dalton Trans. 2008 Feb 28;(8):1081-6.

Frequently Asked Questions

What is the CAS number of Tosyl-L-arginine methyl ester?

The CAS number of Tosyl-L-arginine methyl ester is 901-47-3.

What are the molecular formula and molecular weight of Tosyl-L-arginine methyl ester?

Tosyl-L-arginine methyl ester has molecular formula C14H22N4O4S and molecular weight 342.42 g/mol.

Which suppliers offer Tosyl-L-arginine methyl ester?

1 supplier(s) listed; reference unit price ¥10.24–10.60 /mg.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tosyl-L-arginine methyl ester (CAS 901-47-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1971297-6 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.