4,5-Dimethoxycanthin-6-one

Also known as: Methylnigakinone, Nigakinon-methylether, 4,5-Dimethoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one, 4,5-Dimethoxy-canthin-6-on, 6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 4,5-dimethoxy-

4,5-Dimethoxycanthin-6-one (CAS 18110-87-7) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C16H12N2O3 and a molecular weight of 280.278 g/mol. Key properties include a melting point of 145-146 °C, a boiling point of 455.1±45.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 229.0±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 18110-87-7
Jingsj CID: J-1971183-2
Molecular Formula: C₁₆H₁₂N₂O₃
Molecular Weight: 280.278 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	145-146 °C
Boiling Point	455.1±45.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	229.0±28.7 °C
Exact Mass	280.084778
PSA	52.83000
LogP	2.16
Vapor Pressure	0.0±1.1 mmHg at 25°C
Refractive Index	1.688

Activity & Biological Data

Target	CYP1A2:1.7 μM (IC50) CYP1A2:2.6 μM (Ki)
Additional Information	[1]. Taichi O, et al. Studies on the Constituents of Picrasma quassioides BENNET. III. The Alkaloidal Constituents [2]. Miao X,et al. In vitro metabolism of 4, 5-dimethoxycanthin-6-one by human liver microsomes and its inhibition on human CYP1A2. Life Sci. 2017;190:46-51.

Frequently Asked Questions

What is the CAS number of 4,5-Dimethoxycanthin-6-one?

The CAS number of 4,5-Dimethoxycanthin-6-one is 18110-87-7.

What are the molecular formula and molecular weight of 4,5-Dimethoxycanthin-6-one?

4,5-Dimethoxycanthin-6-one has molecular formula C16H12N2O3 and molecular weight 280.278 g/mol.

What are the upstream and downstream products of 4,5-Dimethoxycanthin-6-one?

For 4,5-Dimethoxycanthin-6-one, Upstream Products: Diazomethane, Nigakinone; Downstream Products: 1-Methoxycarbonyl-beta-carboline, 1-(Hydroxymethyl)-β-carboline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "4,5-Dimethoxycanthin-6-one (CAS 18110-87-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1971183-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.