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L-γ-glutamyl-L-cysteine

Also known as: gamma-glutamylcysteine, γ-glutamylcysteine, Glutathione Impurity D, des-Gly-glutathione reduced form, L-gamma-glutamyl-L-cysteine, (2S)-2-amino-5-[[(1R)-1-carboxy-2-sulfanylethyl]amino]-5-oxopentanoic acid, (S)-2-amino-5-(((R)-1-carboxy-2-mercaptoethyl)amino)-5-oxopentanoic acid, 5-L-Glutamyl-L-cysteine, g-L-Glutamyl-L-cysteine

L-γ-glutamyl-L-cysteine (CAS 636-58-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H14N2O5S and a molecular weight of 250.27200 g/mol. Key properties include a melting point of 167℃, a boiling point of 592.4ºC at 760 mmHg, a density of 1.436g/cm3 and a flash point of 312.1ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
636-58-8
Jingsj CID
J-1971051-1
Molecular Formula
C8H14N2O5S
Molecular Weight
250.27200 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point167℃
Boiling Point592.4ºC at 760 mmHg
Density1.436g/cm3
Flash Point312.1ºC
Exact Mass250.06200
PSA168.52000
Refractive Index1.57
Storage Conditions−20°C

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetHuman Endogenous Metabolite
Additional Information[1]. Braidy N, et al. The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ40 Oligomers in Human Astrocytes. Front Aging Neurosci. 2019 Aug 8;11:177.

Frequently Asked Questions

What is the CAS number of L-γ-glutamyl-L-cysteine?

The CAS number of L-γ-glutamyl-L-cysteine is 636-58-8.

What are the molecular formula and molecular weight of L-γ-glutamyl-L-cysteine?

L-γ-glutamyl-L-cysteine has molecular formula C8H14N2O5S and molecular weight 250.27200 g/mol.

Is L-γ-glutamyl-L-cysteine hazardous?

L-γ-glutamyl-L-cysteine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of L-γ-glutamyl-L-cysteine?

For L-γ-glutamyl-L-cysteine, Upstream Products: N-Phthaloyl-L-glutamic anhydride, L-Cysteine, L-(+)Sodium glutamate; Downstream Products: L-Cysteine, Glutathione.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "L-γ-glutamyl-L-cysteine (CAS 636-58-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1971051-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.