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4-(Trifluoromethyl)-1H-pyrazole

Also known as: 1H-Pyrazole, 4-(trifluoromethyl)-, 4-Trifluoromethyl-1H-pyrazole, 4-Trifluoromethylpyrazole, 4-(Trifluoromethyl)pyrazole, 4-(TRIFLUOROMETHYL)-1H-PYRAZOL

4-(Trifluoromethyl)-1H-pyrazole (CAS 52222-73-8) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C4H3F3N2 and a molecular weight of 136.08 g/mol. Key properties include a melting point of 76 °C, a boiling point of 177.7±35.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 61.3±25.9 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
52222-73-8
Jingsj CID
J-1970965-0
Molecular Formula
C4H3F3N2
Molecular Weight
136.08 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point76 °C
Boiling Point177.7±35.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point61.3±25.9 °C
Exact Mass136.024826
PSA28.68000
LogP1.29
Vapor Pressure1.4±0.3 mmHg at 25°C
Refractive Index1.417

GHS Safety & Compliance

Acute ToxicitySignal word: Danger
  • H301 — Toxic if swallowed
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933199090
Summary2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 4-(Trifluoromethyl)-1H-pyrazole?

The CAS number of 4-(Trifluoromethyl)-1H-pyrazole is 52222-73-8.

What are the molecular formula and molecular weight of 4-(Trifluoromethyl)-1H-pyrazole?

4-(Trifluoromethyl)-1H-pyrazole has molecular formula C4H3F3N2 and molecular weight 136.08 g/mol.

Is 4-(Trifluoromethyl)-1H-pyrazole hazardous?

4-(Trifluoromethyl)-1H-pyrazole has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 4-(Trifluoromethyl)-1H-pyrazole?

For 4-(Trifluoromethyl)-1H-pyrazole, Upstream Products: 3,3,3-Trifluoropropanal, (Chloromethylene)dimethyliminium chloride.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-(Trifluoromethyl)-1H-pyrazole (CAS 52222-73-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1970965-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.