Fmoc-Ser(TBDMS)-OH

Also known as: Fmoc-Ser(TBDMS)-OH, Fmoc-Ser(TBS), Fmoc-O-tert-butyldimethylsilyl-L-serine, Fmoc-Ser(bsi)-OH, N-alpha-(9-Fluorenylmethoxycarbonyl)-O-tert-butyldimethylsilyl-L-serine, O-[(1,1-Dimethylethyl)dimethylsilyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine, O-[Dimethyl(2-methyl-2-propanyl)silyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-serine, L-Serine, O-[(1,1-dimethylethyl)dimethylsilyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

Fmoc-Ser(TBDMS)-OH (CAS 146346-81-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C24H31NO5Si and a molecular weight of 441.592 g/mol. Key properties include a boiling point of 571.4±50.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 299.4±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 146346-81-8
Jingsj CID: J-1970623-1
Molecular Formula: C₂₄H₃₁NO₅Si
Molecular Weight: 441.592 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	571.4±50.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	299.4±30.1 °C
Exact Mass	441.197144
PSA	84.86000
LogP	6.80
Vapor Pressure	0.0±1.7 mmHg at 25°C
Refractive Index	1.549

Activity & Biological Data

Additional Information	[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Frequently Asked Questions

What is the CAS number of Fmoc-Ser(TBDMS)-OH?

The CAS number of Fmoc-Ser(TBDMS)-OH is 146346-81-8.

What are the molecular formula and molecular weight of Fmoc-Ser(TBDMS)-OH?

Fmoc-Ser(TBDMS)-OH has molecular formula C24H31NO5Si and molecular weight 441.592 g/mol.

What are the upstream and downstream products of Fmoc-Ser(TBDMS)-OH?

For Fmoc-Ser(TBDMS)-OH, Upstream Products: tert-Butyldimethylchlorosilane, Fmoc-Ser-OH, Fmoc-OSu; Downstream Products: Fmoc-Ser-OH.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Fmoc-Ser(TBDMS)-OH (CAS 146346-81-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1970623-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.