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3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone

Also known as: Mdivi-1, Mitochondrial division inhibitor 1, 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, 3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanylidene-1H-quinazolin-4-one, 3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanylquinazolin-4(3H)-one, 4(1H)-Quinazolinone, 3-(2,4-dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-

3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone (CAS 338967-87-6) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C15H10Cl2N2O2S and a molecular weight of 353.223 g/mol. Key properties include a melting point of 289 °C, a boiling point of 522.5±60.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 269.8±32.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
338967-87-6
Jingsj CID
J-1969524-0
Molecular Formula
C15H10Cl2N2O2S
Molecular Weight
353.223 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point289 °C
Boiling Point522.5±60.0 °C at 760 mmHg
Density1.6±0.1 g/cm3
Flash Point269.8±32.9 °C
Exact Mass351.984009
PSA82.92000
LogP3.85
Vapor Pressure0.0±1.4 mmHg at 25°C
Refractive Index1.729
Storage ConditionsStore at -20°C
Additional PropertyDMSO: >20mg/mL

Activity & Biological Data

Additional Information[1]. Cassidy-Stone A, et al. Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Dev Cell. 2008 Feb;14(2):193-204. [2]. Tanaka A, et al. A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis. Mol Cell. 2008 Feb 29;29(4):409-10. [3]. Park SW, et al. A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina. Invest Ophthalmol Vis Sci. 2011 Apr 27;52(5):2837-43. [4]. Zhou K, et al. RIP1-RIP3-DRP1 pathway regulates NLRP3 inflammasome activation following subarachnoid hemorrhage. Exp Neurol. 2017 Sep;295:116-124.

Frequently Asked Questions

What is the CAS number of 3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone?

The CAS number of 3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone is 338967-87-6.

What are the molecular formula and molecular weight of 3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone?

3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone has molecular formula C15H10Cl2N2O2S and molecular weight 353.223 g/mol.

What are the upstream and downstream products of 3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone?

For 3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone, Upstream Products: 2-Nitrobenzoyl chloride, 2,4-Dichloro-5-methoxyaniline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "3-(2,4-Dichloro-5-methoxyphenyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone (CAS 338967-87-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1969524-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.