Torcetrapib

Also known as: Torcetrapib, CP-529414, CP 529414, CS-156, Torcetropib, Ethyl (2R,4S)-4-{[3,5-bis(trifluoromethyl)benzyl](methoxycarbonyl)amino}-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate, 1(2H)-Quinolinecarboxylic acid, 4-[[[3,5-bis(trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-

Torcetrapib (CAS 262352-17-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C26H25F9N2O4 and a molecular weight of 600.47 g/mol. Key properties include a melting point of 54-58ºC, a boiling point of 504.8±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 259.1±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 262352-17-0
Jingsj CID: J-1969492-9
Molecular Formula: C₂₆H₂₅F₉N₂O₄
Molecular Weight: 600.47 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	54-58ºC
Boiling Point	504.8±50.0 °C at 760 mmHg
Density	1.4±0.1 g/cm3
Flash Point	259.1±30.1 °C
PSA	59.08000
LogP	7.76
Vapor Pressure	0.0±1.3 mmHg at 25°C
Refractive Index	1.512
Storage Conditions	Store at RT

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Additional Information	[1]. Clark RW, et al. Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):490-7. [2]. Hu X, et al. Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition. Endocrinology. 2009 May;150(5):2211-9. [3]. Barter PJ, et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007 Nov 22;357(21):2109-22. [4]. Morehouse LA, et al. Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits. J Lipid Res. 2007 Jun;48(6):1263-72.

Additional Information

[1]. Clark RW, et al. Raising high-density lipoprotein in humans through inhibition of cholesteryl ester transfer protein: an initial multidose study of torcetrapib. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):490-7. [2]. Hu X, et al. Torcetrapib induces aldosterone and cortisol production by an intracellular calcium-mediated mechanism independently of cholesteryl ester transfer protein inhibition. Endocrinology. 2009 May;150(5):2211-9. [3]. Barter PJ, et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007 Nov 22;357(21):2109-22. [4]. Morehouse LA, et al. Inhibition of CETP activity by torcetrapib reduces susceptibility to diet-induced atherosclerosis in New Zealand White rabbits. J Lipid Res. 2007 Jun;48(6):1263-72.

Frequently Asked Questions

What is the CAS number of Torcetrapib?

The CAS number of Torcetrapib is 262352-17-0.

What are the molecular formula and molecular weight of Torcetrapib?

Torcetrapib has molecular formula C26H25F9N2O4 and molecular weight 600.47 g/mol.

Is Torcetrapib hazardous?

Torcetrapib has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Torcetrapib?

For Torcetrapib, Upstream Products: 3,5-Bis(trifluoromethyl)benzyl bromide, 4-(Trifluoromethyl)aniline, (R)-3-Aminopentanenitrile.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Torcetrapib (CAS 262352-17-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1969492-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.