5,6-Dihydroxyindole

Also known as: 1H-Indole-5,6-diol, 5,6-Dihydroxy-1H-indole, Indole-5,6-diol, Dopamine lutine, DIHYDROXYINDOLE

5,6-Dihydroxyindole (CAS 3131-52-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C8H7NO2 and a molecular weight of 149.147 g/mol. Key properties include a boiling point of 411.2±25.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 202.5±23.2 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 3131-52-0
Jingsj CID: J-1968864-3
Molecular Formula: C₈H₇NO₂
Molecular Weight: 149.147 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	411.2±25.0 °C at 760 mmHg
Density	1.5±0.1 g/cm3
Flash Point	202.5±23.2 °C
Exact Mass	149.047684
PSA	56.25000
LogP	0.37
Vapor Pressure	0.0±1.0 mmHg at 25°C
Refractive Index	1.802
Storage Conditions	2-8°C

Activity & Biological Data

Target	Human Endogenous Metabolite
Additional Information	[1]. Zhao P, et al. Antiviral, anti-parasitic, and cytotoxic effects of 5,6-dihydroxyindole (DHI), a reactive compound generated by phenoloxidase during insect immune response. Insect Biochem Mol Biol. 2011 Sep;41(9):645-52. [2]. Heiduschka P, et al. Melanin precursor 5,6-dihydroxyindol: protective effects and cytotoxicity on retinal cells in vitroand in vivo. Toxicol Pathol. 2007 Dec;35(7):1030-8.

Target

Human Endogenous Metabolite

Additional Information

[1]. Zhao P, et al. Antiviral, anti-parasitic, and cytotoxic effects of 5,6-dihydroxyindole (DHI), a reactive compound generated by phenoloxidase during insect immune response. Insect Biochem Mol Biol. 2011 Sep;41(9):645-52. [2]. Heiduschka P, et al. Melanin precursor 5,6-dihydroxyindol: protective effects and cytotoxicity on retinal cells in vitroand in vivo. Toxicol Pathol. 2007 Dec;35(7):1030-8.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 5,6-Dihydroxyindole?

The CAS number of 5,6-Dihydroxyindole is 3131-52-0.

What are the molecular formula and molecular weight of 5,6-Dihydroxyindole?

5,6-Dihydroxyindole has molecular formula C8H7NO2 and molecular weight 149.147 g/mol.

What are the upstream and downstream products of 5,6-Dihydroxyindole?

For 5,6-Dihydroxyindole, Upstream Products: 5,6-Diacetoxyindole, Levodopa, 5,6-Dibenzyloxyindole; Downstream Products: 5,6-Diacetoxyindole, 4-Hydroxyindole, 1H-Pyrrole-2,3,5-tricarboxylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5,6-Dihydroxyindole (CAS 3131-52-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1968864-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.