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S-Nitroso-L-glutathione

Also known as: S-Nitrosoglutathione, GSNO, Nitrosoglutathione, S-Nitrosylglutathione, L-γ-Glutamyl-S-nitroso-L-cysteinylglycine, N-(N-L-γ-Glutamyl-S-nitroso-L-cysteinyl)glycine, RVC 588, Glutathione thionitrite

S-Nitroso-L-glutathione (CAS 57564-91-7) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C10H16N4O7S and a molecular weight of 336.322 g/mol. Key properties include a melting point of >170ºC (dec.) and a density of 1.7±0.1 g/cm3. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.
57564-91-7
Jingsj CID
J-1966301-5
Molecular Formula
C10H16N4O7S
Molecular Weight
336.322 g/mol
Category
Pharma Intermediates
Last updated
11/3/2026
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Physicochemical Properties

Melting Point>170ºC (dec.)
Density1.7±0.1 g/cm3
Exact Mass336.073975
PSA213.55000
LogP-0.26
Refractive Index1.656

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Marie-Lynda Bouressam, et al. S-nitrosoglutathione inhibits cerebrovascular angiotensin II-dependent and -independent AT 1 receptor responses: A possible role of S-nitrosation. Br J Pharmacol. 2019 Jun;176(12):2049-2062. [2]. D E Jensen, et al. S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme. Biochem J. 1998 Apr 15;331 ( Pt 2)(Pt 2):659-68. [3]. Caneta Brown, et al. The effects of S-nitrosoglutathione and S-nitroso-N-acetyl-D, L-penicillamine in a rat model of pre-eclampsia. J Nat Sci Biol Med. 2013 Jul;4(2):330-5. [4]. Yur-Ren Kuo, et al. Nitrosoglutathione promotes flap survival via suppression of reperfusion injury-induced superoxide and inducible nitric oxide synthase induction. J Trauma. 2004 Nov;57(5):1025-31. [5]. Eva Nozik-Grayck, et al. Pulmonary vasoconstriction by serotonin is inhibited by S-nitrosoglutathione. Am J Physiol Lung Cell Mol Physiol. 2002 May;282(5):L1057-65.

Customs & Trade Information

HS Code2930909090
Summary2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of S-Nitroso-L-glutathione?

The CAS number of S-Nitroso-L-glutathione is 57564-91-7.

What are the molecular formula and molecular weight of S-Nitroso-L-glutathione?

S-Nitroso-L-glutathione has molecular formula C10H16N4O7S and molecular weight 336.322 g/mol.

Is S-Nitroso-L-glutathione hazardous?

S-Nitroso-L-glutathione has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of S-Nitroso-L-glutathione?

For S-Nitroso-L-glutathione, Upstream Products: Glutathione, tert-Butyl nitrite, Isopropyl nitrite; Downstream Products: N-Nitrosomorpholine, Glutathione disulfide, Glutathione.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "S-Nitroso-L-glutathione (CAS 57564-91-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1966301-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.