Desethylamiodarone hydrochloride

Also known as: N-Desethylamiodarone hydrochloride, Amiodarone EP Impurity B, Amiodarone Impurity B (EP), Amiodarone Related Compound B (USP), (2-Butylbenzofuran-3-yl)(4-(2-(ethylamino)ethoxy)-3,5-diiodophenyl)methanone hydrochloride, 2-Butyl-3-benzofuranyl-4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride, Mono-N-desethylamiodarone hydrochloride

Desethylamiodarone hydrochloride (CAS 96027-74-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C23H26ClI2NO3 and a molecular weight of 653.719 g/mol. Key properties include a melting point of 176-178ºC, a boiling point of 630.3ºC at 760 mmHg and a flash point of 335ºC. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 96027-74-6
Jingsj CID: J-1965239-2
Molecular Formula: C₂₃H₂₆ClI₂NO₃
Molecular Weight: 653.719 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	176-178ºC
Boiling Point	630.3ºC at 760 mmHg
Flash Point	335ºC
Exact Mass	652.969055
PSA	51.47000
LogP	7.39680
Storage Conditions	-20°C Freezer, Under Inert Atmosphere
Stability	Moisture Sensitive

GHS Safety & Compliance

Flammable / Acute Toxicity / Health HazardSignal word: Danger

H225 — Highly flammable liquid and vapour
H301 — Toxic if swallowed
H311 — Toxic in contact with skin
H331 — Toxic if inhaled
H370 — Causes damage to organs

Activity & Biological Data

Additional Information	[1]. Shayeganpour A, et al. Determination of the enzyme(s) involved in the metabolism of amiodarone in liver and intestine of rat: the contribution of cytochrome P450 3A isoforms. Drug Metab Dispos. 2006 Jan;34(1):43-50. [2]. Singh, B.N. and E.M. Vaughan Williams, The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br J Pharmacol, 1970. 39(4): p. 657-67. [3]. Rosenbaum, M.B., et al., Clinical efficacy of amiodarone as an antiarrhythmic agent. Am J Cardiol, 1976. 38(7): p. 934-44.

Additional Information

[1]. Shayeganpour A, et al. Determination of the enzyme(s) involved in the metabolism of amiodarone in liver and intestine of rat: the contribution of cytochrome P450 3A isoforms. Drug Metab Dispos. 2006 Jan;34(1):43-50. [2]. Singh, B.N. and E.M. Vaughan Williams, The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br J Pharmacol, 1970. 39(4): p. 657-67. [3]. Rosenbaum, M.B., et al., Clinical efficacy of amiodarone as an antiarrhythmic agent. Am J Cardiol, 1976. 38(7): p. 934-44.

Frequently Asked Questions

What is the CAS number of Desethylamiodarone hydrochloride?

The CAS number of Desethylamiodarone hydrochloride is 96027-74-6.

What are the molecular formula and molecular weight of Desethylamiodarone hydrochloride?

Desethylamiodarone hydrochloride has molecular formula C23H26ClI2NO3 and molecular weight 653.719 g/mol.

Is Desethylamiodarone hydrochloride hazardous?

Desethylamiodarone hydrochloride has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.

What are the upstream and downstream products of Desethylamiodarone hydrochloride?

For Desethylamiodarone hydrochloride, Upstream Products: 2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Desethylamiodarone hydrochloride (CAS 96027-74-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1965239-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.