Glabridin

Also known as: 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, (R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-1,3-benzenediol, 1,3-Benzenediol, 4-[(3R)-3,4-dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-, MFCD03427694

Glabridin (CAS 59870-68-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H20O4 and a molecular weight of 324.37 g/mol. Key properties include a melting point of 154-155ºC, a boiling point of 518.6±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 267.4±30.1 °C. GHS hazard statements: H413. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 59870-68-7
Jingsj CID: J-1963868-7
Molecular Formula: C₂₀H₂₀O₄
Molecular Weight: 324.37 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	154-155ºC
Boiling Point	518.6±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	267.4±30.1 °C
Exact Mass	324.136169
PSA	58.92000
LogP	4.26
Vapor Pressure	0.0±1.4 mmHg at 25°C
Refractive Index	1.623
Storage Conditions	room temp

GHS Safety & Compliance

H413

Activity & Biological Data

Target	PPARγ:6.1 μM (EC50)
Additional Information	[1]. Rebhun JF, et al. Identification of glabridin as a bioactive compound in licorice (Glycyrrhiza glabra L.) extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ). Fitoterapia. 2015 Oct;106:55-61. [2]. Chen CT, et al. Glabridin induces apoptosis and cell cycle arrest in oral cancer cells through the JNK1/2 signaling pathway. Environ Toxicol. 2018 Jun;33(6):679-685. [3]. El-Ashmawy NE, et al. Downregulation of iNOS and elevation of cAMP mediate the anti-inflammatory effect of glabridin in rats with ulcerative colitis. Inflammopharmacology. 2018 Apr;26(2):551-559.

Target

PPARγ:6.1 μM (EC50)

Additional Information

[1]. Rebhun JF, et al. Identification of glabridin as a bioactive compound in licorice (Glycyrrhiza glabra L.) extract that activates human peroxisome proliferator-activated receptor gamma (PPARγ). Fitoterapia. 2015 Oct;106:55-61. [2]. Chen CT, et al. Glabridin induces apoptosis and cell cycle arrest in oral cancer cells through the JNK1/2 signaling pathway. Environ Toxicol. 2018 Jun;33(6):679-685. [3]. El-Ashmawy NE, et al. Downregulation of iNOS and elevation of cAMP mediate the anti-inflammatory effect of glabridin in rats with ulcerative colitis. Inflammopharmacology. 2018 Apr;26(2):551-559.

Customs & Trade Information

HS Code	2942000000

Frequently Asked Questions

What is the CAS number of Glabridin?

The CAS number of Glabridin is 59870-68-7.

What are the molecular formula and molecular weight of Glabridin?

Glabridin has molecular formula C20H20O4 and molecular weight 324.37 g/mol.

Is Glabridin hazardous?

Glabridin has GHS hazard statements H413.

What are the upstream and downstream products of Glabridin?

For Glabridin, Upstream Products: 1,3-Dimethoxybenzene, 2',4'-Dimethoxyacetophenone, Resorcinol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Glabridin (CAS 59870-68-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963868-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.