Pomalidomide
Also known as: 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-, 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide, 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione, 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione, ActiMid, CC-4047, Pomalyst
Pomalidomide (CAS 19171-19-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C13H11N3O4 and a molecular weight of 273.244 g/mol. Key properties include a melting point of 318.5 - 320.5°, a boiling point of 582.9±45.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 306.3±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 19171-19-8
- Jingsj CID
- J-1963216-7
- Molecular Formula
- C13H11N3O4
- Molecular Weight
- 273.244 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 318.5 - 320.5° |
|---|---|
| Boiling Point | 582.9±45.0 °C at 760 mmHg |
| Density | 1.6±0.1 g/cm3 |
| Flash Point | 306.3±28.7 °C |
| Exact Mass | 273.074951 |
| PSA | 109.57000 |
| LogP | -0.74 |
| Appearance | yellow |
| Vapor Pressure | 0.0±1.6 mmHg at 25°C |
| Refractive Index | 1.691 |
| Storage Conditions | 2-8°C |
| Additional Property | DMSO: ≥14mg/mL |
Activity & Biological Data
| Target | IC50: 13 nM (TNF-α, in PBMCs)[1] |
|---|---|
| Additional Information | [1]. Zhu YX, et al. Molecular mechanism of action of the immune-modulatory drugs, thalidomide, lenalidomide and pomalidomide in multiple myeloma. Leuk Lymphoma. 2013 Apr;54(4):683-7. [2]. Hernandez-Ilizaliturri FJ1, et al. Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model. Clin Cancer Res. 2005 Aug 15;11(16):5984-92. [3]. Schafer PH, et al. Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs. J Pharmacol Exp Ther. 2003 Jun;305(3):1222-32. [4]. Li Z, et al. Pomalidomide shows significant therapeutic activity against CNS lymphoma with a major impact on the tumor microenvironment in murine models. PLoS One. 2013 Aug 5;8(8):e71754. [5]. Liu D, et al. Tumour necrosis factor-α inhibits hepatic lipid deposition through GSK-3β/β-catenin signaling in juvenile turbot (Scophthalmus maximus L.). Gen Comp Endocrinol. 2016 Mar 1;228:1-8. |
Customs & Trade Information
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Pomalidomide?
The CAS number of Pomalidomide is 19171-19-8.
What are the molecular formula and molecular weight of Pomalidomide?
Pomalidomide has molecular formula C13H11N3O4 and molecular weight 273.244 g/mol.
What are the upstream and downstream products of Pomalidomide?
For Pomalidomide, Upstream Products: 4-Nitrothalidomide, 3-Aminopiperidine-2,6-dione hydrochloride, 3-Aminophthalic acid hydrochloride.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Pomalidomide (CAS 19171-19-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963216-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.