Telaprevir

Also known as: VX-950, Incivek, Incivo, LY 570310, MP 424, VRT 111950

Telaprevir (CAS 402957-28-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C36H53N7O6 and a molecular weight of 679.849 g/mol. Key property: a density of 1.3±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 402957-28-2
Jingsj CID: J-1963209-8
Molecular Formula: C₃₆H₅₃N₇O₆
Molecular Weight: 679.849 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.3±0.1 g/cm3
Exact Mass	679.405762
PSA	179.56000
LogP	3.93
Refractive Index	1.584
Storage Conditions	2~8°C

Activity & Biological Data

Target	Ki: 7 nM (genotype 1 HCV NS3-4A protease)[1]
Additional Information	[1]. Lin K, et al. VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCv replicon cells. Antimicrob Agents Chemother. 2006 May;50(5):1813-22. [2]. Perni RB, et al. Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease. Antimicrob Agents Chemother. 2006 Mar;50(3):899-909. [3]. Zhang X, et al. Discovery and evolution of aloperine derivatives as a new family of HCV inhibitors with novel mechanism. Eur J Med Chem. 2018 Jan 1;143:1053-1065.

Target

Ki: 7 nM (genotype 1 HCV NS3-4A protease)[1]

Additional Information

[1]. Lin K, et al. VX-950, a novel hepatitis C virus (HCV) NS3-4A protease inhibitor, exhibits potent antiviral activities in HCv replicon cells. Antimicrob Agents Chemother. 2006 May;50(5):1813-22. [2]. Perni RB, et al. Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease. Antimicrob Agents Chemother. 2006 Mar;50(3):899-909. [3]. Zhang X, et al. Discovery and evolution of aloperine derivatives as a new family of HCV inhibitors with novel mechanism. Eur J Med Chem. 2018 Jan 1;143:1053-1065.

Frequently Asked Questions

What is the CAS number of Telaprevir?

The CAS number of Telaprevir is 402957-28-2.

What are the molecular formula and molecular weight of Telaprevir?

Telaprevir has molecular formula C36H53N7O6 and molecular weight 679.849 g/mol.

What are the upstream and downstream products of Telaprevir?

For Telaprevir, Upstream Products: (2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoic acid, (1S,3aR,6aS)-ethyl octahydrocyclopenta[c]pyrrole-1-carboxylate, 2-Pyrazinecarboxylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Telaprevir (CAS 402957-28-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963209-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.