Plerixafor

Also known as: AMD3100, Mozobil, 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene, 1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane, 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane, Sdz sid 791, Unii-S915p5499n

Plerixafor (CAS 110078-46-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C28H54N8 and a molecular weight of 502.782 g/mol. Key properties include a melting point of 122-125°C, a boiling point of 657.5±55.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 361.8±26.2 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 110078-46-1
Jingsj CID: J-1963040-1
Molecular Formula: C₂₈H₅₄N₈
Molecular Weight: 502.782 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	122-125°C
Boiling Point	657.5±55.0 °C at 760 mmHg
Density	1.0±0.1 g/cm3
Flash Point	361.8±26.2 °C
Exact Mass	502.447144
PSA	78.66000
LogP	0.20
Vapor Pressure	0.0±2.0 mmHg at 25°C
Refractive Index	1.492
Storage Conditions	Refrigerator

Activity & Biological Data

Target	125I-CXCL12-CXCR4:44 nM (IC50)
Additional Information	[1]. Zabel BA, et al. Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands. J Immunol. 2009 Sep 1;183(5):3204-11. [2]. Mercurio L, et al. Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma model. J Exp Clin Cancer Res. 2016 Mar 25;35:55. [3]. Yang J, et al. Continuous AMD3100 Treatment Worsens Renal Fibrosis through Regulation of Bone Marrow Derived Pro-Angiogenic Cells Homing and T-Cell-Related Inflammation. PLoS One. 2016 Feb 22;11(2):e0149926. [4]. Chu PY, et al. CXCR4 Antagonism Attenuates the Development of Diabetic Cardiac Fibrosis. PLoS One. 2015 Jul 27;10(7):e0133616. [5]. He G, et al. SDF-1 in Mammary Fibroblasts of Bovine with Mastitis Induces EMT and Inflammatory Response of Epithelial Cells. Int J Biol Sci. 2017 May 5;13(5):604-614. [6]. Wei He, et al. Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells. Oncol Lett. 2018 Sep;16(3):3976-3982.

Target

125I-CXCL12-CXCR4:44 nM (IC50)

Additional Information

[1]. Zabel BA, et al. Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands. J Immunol. 2009 Sep 1;183(5):3204-11. [2]. Mercurio L, et al. Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma model. J Exp Clin Cancer Res. 2016 Mar 25;35:55. [3]. Yang J, et al. Continuous AMD3100 Treatment Worsens Renal Fibrosis through Regulation of Bone Marrow Derived Pro-Angiogenic Cells Homing and T-Cell-Related Inflammation. PLoS One. 2016 Feb 22;11(2):e0149926. [4]. Chu PY, et al. CXCR4 Antagonism Attenuates the Development of Diabetic Cardiac Fibrosis. PLoS One. 2015 Jul 27;10(7):e0133616. [5]. He G, et al. SDF-1 in Mammary Fibroblasts of Bovine with Mastitis Induces EMT and Inflammatory Response of Epithelial Cells. Int J Biol Sci. 2017 May 5;13(5):604-614. [6]. Wei He, et al. Targeting CXC motif chemokine receptor 4 inhibits the proliferation, migration and angiogenesis of lung cancer cells. Oncol Lett. 2018 Sep;16(3):3976-3982.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Plerixafor?

The CAS number of Plerixafor is 110078-46-1.

What are the molecular formula and molecular weight of Plerixafor?

Plerixafor has molecular formula C28H54N8 and molecular weight 502.782 g/mol.

What are the upstream and downstream products of Plerixafor?

For Plerixafor, Upstream Products: 1,4-Bis(bromomethyl)benzene, 1,4,8,11-Tetraazacyclotetradecane, cis-decahydro-1H,6H-3a,5a,8a,10a-tetraazapyrene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Plerixafor (CAS 110078-46-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1963040-1 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.