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Ritonavir

Also known as: ABT-538, A-84538, Norvir, RTV, Abbott 84538, NSC 693184, Ritovir, Novir, Ritomune, Viriton, 1,3-thiazol-5-ylmethyl [(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate, 10-Hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic acid 5-thiazolylmethyl ester

Ritonavir (CAS 155213-67-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C37H48N6O5S2 and a molecular weight of 720.944 g/mol. Key properties include a melting point of 120-122°C, a boiling point of 947.0±65.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 526.6±34.3 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
155213-67-5
Jingsj CID
J-1961937-6
Molecular Formula
C37H48N6O5S2
Molecular Weight
720.944 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point120-122°C
Boiling Point947.0±65.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point526.6±34.3 °C
Exact Mass720.312744
PSA202.26000
LogP5.28
Vapor Pressure0.0±0.3 mmHg at 25°C
Refractive Index1.600
Storage Conditions-20°C Freezer

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H312 — Harmful in contact with skin
  • H332 — Harmful if inhaled

Activity & Biological Data

Additional Information[1]. Eagling VA, et al. Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir. Br J Clin Pharmacol. 1997 Aug;44(2):190-4. [2]. Kumar GN, et al. Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J Pharmacol Exp Ther. 1996 Apr;277(1):423-31. [3]. Weichold FF, et al. HIV-1 protease inhibitor ritonavir modulates susceptibility to apoptosis of uninfected T cells. J Hum Virol. 1999 Sep-Oct;2(5):261-9. [4]. Drewe J, et al. HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833. Biochem Pharmacol. 1999 May 15;57(10):1147-52. [5]. Kumar GN, et al. Potent inhibition of the cytochrome P-450 3A-mediated human liver microsomal metabolism of a novel HIV protease inhibitor by ritonavir: A positive drug-drug interaction. Drug Metab Dispos. 1999 Aug;27(8):902-8.

Customs & Trade Information

HS Code2942000000

Frequently Asked Questions

What is the CAS number of Ritonavir?

The CAS number of Ritonavir is 155213-67-5.

What are the molecular formula and molecular weight of Ritonavir?

Ritonavir has molecular formula C37H48N6O5S2 and molecular weight 720.944 g/mol.

Is Ritonavir hazardous?

Ritonavir has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.

What are the upstream and downstream products of Ritonavir?

For Ritonavir, Upstream Products: (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane, L-Valine methyl ester hydrochloride, 4-nitrophenyl 1,3-thiazol-5-ylmethyl carbonate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Ritonavir (CAS 155213-67-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961937-6 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.