Doxazosin

Also known as: UK 33274, UK 33,274, Cardura, Cardura-1, Cardura-2, Cardura-4, Doxazosine, Doxazosina, Doxazosinum, Normothen, 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine, 4-Amino-2-[4-(1,4-benzodioxan-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazoline, MFCD00800482

Doxazosin (CAS 74191-85-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C23H25N5O5 and a molecular weight of 451.48 g/mol. Key properties include a melting point of 289-290°C, a boiling point of 718ºC at 760 mmHg, a density of 1.371 g/cm3 and a flash point of 388ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 74191-85-8
Jingsj CID: J-19619-0
Molecular Formula: C₂₃H₂₅N₅O₅
Molecular Weight: 451.48 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	289-290°C
Boiling Point	718ºC at 760 mmHg
Density	1.371 g/cm3
Flash Point	388ºC
PSA	175.02000
LogP	2.88670
Storage Conditions	-20℃

Activity & Biological Data

Additional Information	[1]. Sun, J.A., et al., Stereoselective binding of doxazosin enantiomers to plasma proteins from rats, dogs and humans in vitro. Acta Pharmacol Sin, 2013. 34(12): p. 1568-74. [2]. D'Eletto, R.D. and N.B. Javitt, Effect of doxazosin on cholesterol synthesis in cell culture. J Cardiovasc Pharmacol, 1989. 13 Suppl 2: p. S1-4; discussion S4. [3]. Miura, Y. and K. Yoshinaga, Doxazosin: a newly developed, selective alpha 1-inhibitor in the management of patients with pheochromocytoma. Am Heart J, 1988. 116(6 Pt 2): p. 1785-9.

Additional Information

[1]. Sun, J.A., et al., Stereoselective binding of doxazosin enantiomers to plasma proteins from rats, dogs and humans in vitro. Acta Pharmacol Sin, 2013. 34(12): p. 1568-74. [2]. D'Eletto, R.D. and N.B. Javitt, Effect of doxazosin on cholesterol synthesis in cell culture. J Cardiovasc Pharmacol, 1989. 13 Suppl 2: p. S1-4; discussion S4. [3]. Miura, Y. and K. Yoshinaga, Doxazosin: a newly developed, selective alpha 1-inhibitor in the management of patients with pheochromocytoma. Am Heart J, 1988. 116(6 Pt 2): p. 1785-9.

Frequently Asked Questions

What is the CAS number of Doxazosin?

The CAS number of Doxazosin is 74191-85-8.

What are the molecular formula and molecular weight of Doxazosin?

Doxazosin has molecular formula C23H25N5O5 and molecular weight 451.48 g/mol.

What are the upstream and downstream products of Doxazosin?

For Doxazosin, Upstream Products: 2-Chloro-4-amino-6,7-dimethoxyquinazoline, 1-(1,4-Benzodioxane-2-carbonyl)piperazine, 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Doxazosin (CAS 74191-85-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-19619-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.