Saquinavir
Also known as: Ro 31-8959, Ro 31-8959/000, Fortovase, Invirase, Sch 52852, MFCD00866925, N1-{(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl]-3-hydroxy-1-phenylbutan-2-yl}-N2-(quinolin-2-ylcarbonyl)-L-aspartamide, (2S)-N-{(1S,2R)-1-benzyl-3-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl]-2-hydroxypropyl}-2-[(quinolin-2-ylcarbonyl)amino]butanediamide, N-{(2S,3R)-3-Hydroxy-4-[(3S,4aS,8aS)-3-[(2-methyl-2-propanyl)carbamoyl]octahydro-2(1H)-isoquinolinyl]-1-phenyl-2-butanyl}-N-(2-quinolinylcarbonyl)-L-aspartamide, Sequinavir
Saquinavir (CAS 127779-20-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C38H50N6O5 and a molecular weight of 670.841 g/mol. Key properties include a melting point of 91.5ºC, a boiling point of 1015ºC at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 567.7ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 127779-20-8
- Jingsj CID
- J-1961730-2
- Molecular Formula
- C38H50N6O5
- Molecular Weight
- 670.841 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 91.5ºC |
|---|---|
| Boiling Point | 1015ºC at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 567.7ºC |
| Exact Mass | 670.384277 |
| PSA | 166.75000 |
| LogP | 6.40 |
| Vapor Pressure | 0mmHg at 25°C |
| Refractive Index | 1.646 |
| Storage Conditions | 2-8℃ |
Activity & Biological Data
| Additional Information | [1]. Marco Donia, Danijela Maksimovic-Ivanic, Sanja Mijatovic, et al. In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells. Cell cycle. 2011, 1 [2]. Walmsley Sharon, Avihingsanon Anchalee, Slim Jihad et al. Gemini: A Noninferiority Study of Saquinavir/Ritonavir Versus Lopinavir/Ritonavir as Initial HIV-1 Therapy in Adults. JAIDS Journal of Acquired Immune Deficiency Syndromes. 2009,50 (4) :367-374. [3]. Saquinavir [4]. Barillari Giovannia, Iovane Andréa, Bacigalupo Ilariaa, et al. Ritonavir or saquinavir impairs the invasion of cervical intraepithelial neoplasia cells via a reduction of MMP expression and activity. AIDS. 2012, 26 (8): 909-919. [5]. Martha Stefanidou, Carolina Herrera, Naomi Armanasco et al. Saquinavir Inhibits Early Events Associated with Establishment of HIV-1 Infection: Potential Role for Protease Inhibitors in Prevention. Antimicrob. Agents Chemother. 2012, 56 (8): 4381-4390. |
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Frequently Asked Questions
What is the CAS number of Saquinavir?
The CAS number of Saquinavir is 127779-20-8.
What are the molecular formula and molecular weight of Saquinavir?
Saquinavir has molecular formula C38H50N6O5 and molecular weight 670.841 g/mol.
What are the upstream and downstream products of Saquinavir?
For Saquinavir, Upstream Products: N2-(2-Quinolinylcarbonyl)-L-asparagine, (3S,4aS,8aS)-2-[(2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide, L-Phenylalanine; Downstream Products: Saquinavir mesylate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Saquinavir (CAS 127779-20-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961730-2 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.