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Zoledronic acid monohydrate

Also known as: Zoledronic acid hydrate, [1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate, 1-Hydroxy-2-(1-imidazolyl)ethane-1,1-diphosphonic Acid Monohydrate, Zometa, Reclast, Aclasta

Zoledronic acid monohydrate (CAS 165800-06-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C5H12N2O8P2 and a molecular weight of 290.105 g/mol. Key properties include a melting point of 245 °C(dec.), a boiling point of 764ºC at 760 mmHg and a flash point of 415.8ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
165800-06-6
Jingsj CID
J-1961613-8
Molecular Formula
C5H12N2O8P2
Molecular Weight
290.105 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point245 °C(dec.)
Boiling Point764ºC at 760 mmHg
Flash Point415.8ºC
Exact Mass290.006897
PSA181.96000
Vapor Pressure1.53E-24mmHg at 25°C
Storage Conditions2-8°C

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Scheper M, et al. A novel soft-tissue in vitro model for bisphosphonate-associated osteonecrosis. ibrogenesis Tissue Repair. 2010 Apr 1;3:6. [2]. Wang L, et al. The apoptotic effect of Zoledronic acid on the nasopharyngeal carcinoma cells via ROS mediated chloride channel activation. Clin Exp Pharmacol Physiol. 2018 Jun 8.

Customs & Trade Information

HS Code2933290090
Summary2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Zoledronic acid monohydrate?

The CAS number of Zoledronic acid monohydrate is 165800-06-6.

What are the molecular formula and molecular weight of Zoledronic acid monohydrate?

Zoledronic acid monohydrate has molecular formula C5H12N2O8P2 and molecular weight 290.105 g/mol.

Is Zoledronic acid monohydrate hazardous?

Zoledronic acid monohydrate has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Zoledronic acid monohydrate?

For Zoledronic acid monohydrate, Upstream Products: Zoledronic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Zoledronic acid monohydrate (CAS 165800-06-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961613-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.