Manidipine dihydrochloride

Also known as: Manidipine hydrochloride, Manidipine 2HCl, CV-4093 dihydrochloride, Calslot

Manidipine dihydrochloride (CAS 89226-75-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C35H40Cl2N4O6 and a molecular weight of 683.62 g/mol. Key properties include a melting point of 211 °C(dec.) and a boiling point of 722ºC at 760 mmHg. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 89226-75-5
Jingsj CID: J-1961590-8
Molecular Formula: C₃₅H₄₀Cl₂N₄O₆
Molecular Weight: 683.62 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	211 °C(dec.)
Boiling Point	722ºC at 760 mmHg
PSA	116.93000
LogP	6.48280

Activity & Biological Data

Additional Information	[1]. Buset Ríos N, Rodríguez Esparragón F, Fernández-Andrade Rodríguez C, et al. Vascular and metabolic properties of manidipine . Nefrologia. 2011;31(3):268-74. [2]. Costa S, Zimetti F, Pedrelli M, et al. Manidipine reduces pro-inflammatory cytokines secretion in human endothelial cells and macrophages. Pharmacol Res. 2010 Sep;62(3):265-70. [3]. Cavalieri L, Cremonesi G. Metabolic effects of manidipine. Am J Cardiovasc Drugs. 2009;9(3):163-76. doi: 10.2165/00129784-200909030-00004. [4]. Roca-Cusachs A, Triposkiadis F. Antihypertensive effect of manidipine. Drugs. 2005;65 Suppl 2:11-9. [5]. Nagaoka A. Pharmacologic characteristics of a new calcium antagonist, manidipine: beneficial effects on renal circulation and vascular changes. Am Heart J. 1993 Feb;125(2 Pt 2):560-5.

Additional Information

[1]. Buset Ríos N, Rodríguez Esparragón F, Fernández-Andrade Rodríguez C, et al. Vascular and metabolic properties of manidipine . Nefrologia. 2011;31(3):268-74. [2]. Costa S, Zimetti F, Pedrelli M, et al. Manidipine reduces pro-inflammatory cytokines secretion in human endothelial cells and macrophages. Pharmacol Res. 2010 Sep;62(3):265-70. [3]. Cavalieri L, Cremonesi G. Metabolic effects of manidipine. Am J Cardiovasc Drugs. 2009;9(3):163-76. doi: 10.2165/00129784-200909030-00004. [4]. Roca-Cusachs A, Triposkiadis F. Antihypertensive effect of manidipine. Drugs. 2005;65 Suppl 2:11-9. [5]. Nagaoka A. Pharmacologic characteristics of a new calcium antagonist, manidipine: beneficial effects on renal circulation and vascular changes. Am Heart J. 1993 Feb;125(2 Pt 2):560-5.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Manidipine dihydrochloride?

The CAS number of Manidipine dihydrochloride is 89226-75-5.

What are the molecular formula and molecular weight of Manidipine dihydrochloride?

Manidipine dihydrochloride has molecular formula C35H40Cl2N4O6 and molecular weight 683.62 g/mol.

What are the upstream and downstream products of Manidipine dihydrochloride?

For Manidipine dihydrochloride, Upstream Products: Manidipine, 1-Benzhydrylpiperazine, 2-(4-benzhydrylpiperazin-1-yl)ethanol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Manidipine dihydrochloride (CAS 89226-75-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961590-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.