Nucleozin

Also known as: CS-681, Methanone, [4-(2-chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)-, [4-(2-Chloro-4-nitrophenyl)-1-piperazinyl](5-methyl-3-phenyl-4-isoxazolyl)methanone, [4-(2-Chloro-4-nitro-phenyl)-piperazin-1-yl]-(5-methyl-3-phenyl-isoxazol-4-yl)-methanone, 1-(2-Chloro-4-nitrophenyl)-4-[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]-piperazine

Nucleozin (CAS 341001-38-5) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C21H19ClN4O4 and a molecular weight of 426.85300 g/mol. Key properties include a boiling point of 673.8ºC at 760 mmHg, a density of 1.371 and a flash point of 361.3ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 341001-38-5
Jingsj CID: J-1961572-6
Molecular Formula: C₂₁H₁₉ClN₄O₄
Molecular Weight: 426.85300 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	673.8ºC at 760 mmHg
Density	1.371
Flash Point	361.3ºC
Exact Mass	426.10900
PSA	95.40000
LogP	4.70010
Refractive Index	1.631
Storage Conditions	2-8℃

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed

Activity & Biological Data

Additional Information	[1]. Kao, Richard Y. et al. Identification of influenza A nucleoprotein as an antiviral target.Nature Biotechnology (2010), 28(6), 600-605. [2]. Hung HC, Liu CL, Hsu JT, Horng JT, Fang MY, Wu SY, Ueng SH, Wang MY, Yaw CW, Hou MH.Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching.Anal Chem. 2012 Aug 7;84(15):6391-9. Epub 2012 Jul 10. [3]. Su CY, Cheng TJ, Lin MI, Wang SY, Huang WI, Lin-Chu SY, Chen YH, Wu CY, Lai MM, Cheng WC, Wu YT, Tsai MD, Cheng YS, Wong CH.High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity.Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19151-6. Epub 2010 Oct 25. [4]. Kao RY, Yang D, Lau LS, Tsui WH, Hu L, Dai J, Chan MP, Chan CM, Wang P, Zheng BJ, Sun J, Huang JD, Madar J, Chen G, Chen H, Guan Y, Yuen KY.Identification of influenza A nucleoprotein as an antiviral target.Nat Biotechnol. 2010 Jun;28(6):600-5. Epub 2010 May 30.

Additional Information

[1]. Kao, Richard Y. et al. Identification of influenza A nucleoprotein as an antiviral target.Nature Biotechnology (2010), 28(6), 600-605. [2]. Hung HC, Liu CL, Hsu JT, Horng JT, Fang MY, Wu SY, Ueng SH, Wang MY, Yaw CW, Hou MH.Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching.Anal Chem. 2012 Aug 7;84(15):6391-9. Epub 2012 Jul 10. [3]. Su CY, Cheng TJ, Lin MI, Wang SY, Huang WI, Lin-Chu SY, Chen YH, Wu CY, Lai MM, Cheng WC, Wu YT, Tsai MD, Cheng YS, Wong CH.High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity.Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19151-6. Epub 2010 Oct 25. [4]. Kao RY, Yang D, Lau LS, Tsui WH, Hu L, Dai J, Chan MP, Chan CM, Wang P, Zheng BJ, Sun J, Huang JD, Madar J, Chen G, Chen H, Guan Y, Yuen KY.Identification of influenza A nucleoprotein as an antiviral target.Nat Biotechnol. 2010 Jun;28(6):600-5. Epub 2010 May 30.

Frequently Asked Questions

What is the CAS number of Nucleozin?

The CAS number of Nucleozin is 341001-38-5.

What are the molecular formula and molecular weight of Nucleozin?

Nucleozin has molecular formula C21H19ClN4O4 and molecular weight 426.85300 g/mol.

Is Nucleozin hazardous?

Nucleozin has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.

What are the upstream and downstream products of Nucleozin?

For Nucleozin, Upstream Products: 5-Methyl-3-phenylisoxazole-4-carbonyl chloride, 1-(2-Chloro-4-nitrophenyl)piperazine, 5-Methyl-3-phenylisoxazole-4-carboxylic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Nucleozin (CAS 341001-38-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961572-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.