Naringin dihydrochalcone

Also known as: Naringin DC, Naringin dihydrochal, Senior saccharin, Naringin dihydrochalcone (Naringin DC), 1-[4-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone

Naringin dihydrochalcone (CAS 18916-17-1) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C27H34O14 and a molecular weight of 582.55 g/mol. Key properties include a melting point of 131-132°C, a boiling point of 916.8±65.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 302.7±27.8 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 18916-17-1
Jingsj CID: J-1961466-5
Molecular Formula: C₂₇H₃₄O₁₄
Molecular Weight: 582.55 g/mol
Category: Ketones
Last updated: 8/21/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	131-132°C
Boiling Point	916.8±65.0 °C at 760 mmHg
Density	1.6±0.1 g/cm3
Flash Point	302.7±27.8 °C
PSA	236.06000
LogP	3.38
Vapor Pressure	0.0±0.3 mmHg at 25°C
Refractive Index	1.696

Activity & Biological Data

Target	NF-κB
Additional Information	[1]. Chen F, et al. Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction. PLoS One. 2015 Nov 30;10(11):e0143868. [2]. Raha S, et al. Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells. Int J Oncol. 2015 Sep;47(3):1061-9. [3]. Kulasekaran G, et al. Neuroprotective efficacy of naringin on 3-nitropropionic acid-induced mitochondrial dysfunction through the modulation of Nrf2 signaling pathway in PC12 cells. Mol Cell Biochem. 2015 Nov;409(1-2):199-211. [4]. Wang D, et al. Naringin Improves Neuronal Insulin Signaling, Brain Mitochondrial Function, and Cognitive Function in High-Fat Diet-Induced Obese Mice. Cell Mol Neurobiol. 2015 Oct;35(7):1061-71.

Target

NF-κB

Additional Information

[1]. Chen F, et al. Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction. PLoS One. 2015 Nov 30;10(11):e0143868. [2]. Raha S, et al. Naringin induces autophagy-mediated growth inhibition by downregulating the PI3K/Akt/mTOR cascade via activation of MAPK pathways in AGS cancer cells. Int J Oncol. 2015 Sep;47(3):1061-9. [3]. Kulasekaran G, et al. Neuroprotective efficacy of naringin on 3-nitropropionic acid-induced mitochondrial dysfunction through the modulation of Nrf2 signaling pathway in PC12 cells. Mol Cell Biochem. 2015 Nov;409(1-2):199-211. [4]. Wang D, et al. Naringin Improves Neuronal Insulin Signaling, Brain Mitochondrial Function, and Cognitive Function in High-Fat Diet-Induced Obese Mice. Cell Mol Neurobiol. 2015 Oct;35(7):1061-71.

Frequently Asked Questions

What is the CAS number of Naringin dihydrochalcone?

The CAS number of Naringin dihydrochalcone is 18916-17-1.

What are the molecular formula and molecular weight of Naringin dihydrochalcone?

Naringin dihydrochalcone has molecular formula C27H34O14 and molecular weight 582.55 g/mol.

What are the upstream and downstream products of Naringin dihydrochalcone?

For Naringin dihydrochalcone, Upstream Products: Naringin; Downstream Products: Phloretin, Trilobatin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Naringin dihydrochalcone (CAS 18916-17-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961466-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.