Isoorientin

Also known as: Luteolin-6-C-glucoside, Homoorientin, Lespecapitoside, Lespecapittoside, 2-(3,4-Dihydroxyphenyl)-6-β-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one

Isoorientin (CAS 4261-42-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C21H20O11 and a molecular weight of 448.377 g/mol. Key properties include a melting point of 245-246ºC, a boiling point of 856.7±65.0 °C at 760 mmHg, a density of 1.8±0.1 g/cm3 and a flash point of 303.2±27.8 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 4261-42-1
Jingsj CID: J-1961458-5
Molecular Formula: C₂₁H₂₀O₁₁
Molecular Weight: 448.377 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	245-246ºC
Boiling Point	856.7±65.0 °C at 760 mmHg
Density	1.8±0.1 g/cm3
Flash Point	303.2±27.8 °C
Exact Mass	448.100555
PSA	201.28000
LogP	1.58
Appearance	yellow
Vapor Pressure	0.0±0.3 mmHg at 25°C
Refractive Index	1.767
Storage Conditions	2-8°C
Additional Property	methanol: soluble5mg/mL, clear, colorless to yellow

Activity & Biological Data

Target	COX-2:39 μM (IC50)
Additional Information	[1]. Sumalatha M, et al. Isoorientin, a Selective Inhibitor of Cyclooxygenase-2 (COX-2) from the Tubers of Pueraria tuberosa. Nat Prod Commun. 2015 Oct;10(10):1703-4. [2]. Ye T, et al. Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells. Onco Targets Ther. 2016 Dec 12;9:7481-7492. [3]. Anilkumar K, et al. Evaluation of Anti-Inflammatory Properties of Isoorientin Isolated from Tubers of Pueraria tuberosa. Oxid Med Cell Longev. 2017;2017:5498054.

Target

COX-2:39 μM (IC50)

Additional Information

[1]. Sumalatha M, et al. Isoorientin, a Selective Inhibitor of Cyclooxygenase-2 (COX-2) from the Tubers of Pueraria tuberosa. Nat Prod Commun. 2015 Oct;10(10):1703-4. [2]. Ye T, et al. Isoorientin induces apoptosis, decreases invasiveness, and downregulates VEGF secretion by activating AMPK signaling in pancreatic cancer cells. Onco Targets Ther. 2016 Dec 12;9:7481-7492. [3]. Anilkumar K, et al. Evaluation of Anti-Inflammatory Properties of Isoorientin Isolated from Tubers of Pueraria tuberosa. Oxid Med Cell Longev. 2017;2017:5498054.

Frequently Asked Questions

What is the CAS number of Isoorientin?

The CAS number of Isoorientin is 4261-42-1.

What are the molecular formula and molecular weight of Isoorientin?

Isoorientin has molecular formula C21H20O11 and molecular weight 448.377 g/mol.

What are the upstream and downstream products of Isoorientin?

For Isoorientin, Upstream Products: 3,4-Dibenzyloxybenzaldehyde, 2,4,6-Trihydroxyacetophenone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Isoorientin (CAS 4261-42-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1961458-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.