SKF 81297 hydrobromide

Also known as: R(+)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, (R)-6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide, 6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide, 6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide, SKF 81297C, R-(+)-SKF-81297 hydrobromide, 6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, 9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol:hydrobromide, 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-, (1R)-, hydrobromide (1:1)

SKF 81297 hydrobromide (CAS 67287-39-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C16H17BrClNO2 and a molecular weight of 370.669 g/mol. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 67287-39-2
Jingsj CID: J-1960316-8
Molecular Formula: C₁₆H₁₇BrClNO₂
Molecular Weight: 370.669 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Exact Mass	369.013123
PSA	52.49000
LogP	4.31570

Activity & Biological Data

Target	D1 Receptor
Additional Information	[1]. Vermeulen RJ, et al. The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys. Eur J Pharmacol. 1993 Apr 22;235(1):143-7. [2]. Auger ML, et al. Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine. Neuropharmacology. 2020 Jan 1;162:107844.

Target

D1 Receptor

Additional Information

[1]. Vermeulen RJ, et al. The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys. Eur J Pharmacol. 1993 Apr 22;235(1):143-7. [2]. Auger ML, et al. Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine. Neuropharmacology. 2020 Jan 1;162:107844.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of SKF 81297 hydrobromide?

The CAS number of SKF 81297 hydrobromide is 67287-39-2.

What are the molecular formula and molecular weight of SKF 81297 hydrobromide?

SKF 81297 hydrobromide has molecular formula C16H17BrClNO2 and molecular weight 370.669 g/mol.

What are the upstream and downstream products of SKF 81297 hydrobromide?

For SKF 81297 hydrobromide, Upstream Products: Isovanillin, 2-chloro-1-(chloromethyl)-3,4-dimethoxybenzene, 2-Chloro-3,4-dimethoxybenzaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "SKF 81297 hydrobromide (CAS 67287-39-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1960316-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.