Iloperidone
Also known as: 1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]ethanone, Fanapt, Fanapta, HP 873, Zomaril, Iloperidone-P88, 1-(4-{3-[4-(6-Fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethanone
Iloperidone (CAS 133454-47-4) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C24H27FN2O4 and a molecular weight of 426.481 g/mol. Key properties include a melting point of 118-120°C, a boiling point of 593.7±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 312.8±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 133454-47-4
- Jingsj CID
- J-1960119-5
- Molecular Formula
- C24H27FN2O4
- Molecular Weight
- 426.481 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 118-120°C |
|---|---|
| Boiling Point | 593.7±50.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 312.8±30.1 °C |
| Exact Mass | 426.195496 |
| PSA | 64.80000 |
| LogP | 3.81 |
| Appearance | white to beige |
| Vapor Pressure | 0.0±1.7 mmHg at 25°C |
| Refractive Index | 1.570 |
| Storage Conditions | -20°C Freezer, Under Inert Atmosphere |
| Additional Property | DMSO: soluble5mg/mL, clear |
GHS Safety & Compliance
- H225 — Highly flammable liquid and vapour
- H301 — Toxic if swallowed
- H311 — Toxic in contact with skin
- H331 — Toxic if inhaled
- H370 — Causes damage to organs
Activity & Biological Data
| Additional Information | [1]. Kongsamut, S., et al., Iloperidone binding to human and rat dopamine and 5-HT receptors. Eur J Pharmacol, 1996. 317(2-3): p. 417-23. [2]. Sainati, S.M., et al., Safety, tolerability, and effect of food on the pharmacokinetics of iloperidone (HP 873), a potential atypical antipsychotic. J Clin Pharmacol, 1995. 35(7): p. 713-20. [3]. Albers, L.J., A. Musenga, and M.A. Raggi, Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market? Expert Opin Investig Drugs, 2008. 17(1): p. 61-75. |
|---|
Customs & Trade Information
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Iloperidone?
The CAS number of Iloperidone is 133454-47-4.
What are the molecular formula and molecular weight of Iloperidone?
Iloperidone has molecular formula C24H27FN2O4 and molecular weight 426.481 g/mol.
Is Iloperidone hazardous?
Iloperidone has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.
What are the upstream and downstream products of Iloperidone?
For Iloperidone, Upstream Products: Apocynin, 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride, 1-Bromo-3-chloropropane; Downstream Products: Hydroxy Iloperidone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Iloperidone (CAS 133454-47-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1960119-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.