Trabectedin

Also known as: ET-743, Yondelis, Ecteinascidin 743, Ecteinascidine 743, ecteinascidin-743, NSC-684766, UNII-ID0YZQ2TCP

Trabectedin (CAS 114899-77-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C39H43N3O11S and a molecular weight of 761.837 g/mol. Key property: a density of 1.6±0.1 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 114899-77-3
Jingsj CID: J-1960074-9
Molecular Formula: C₃₉H₄₃N₃O₁₁S
Molecular Weight: 761.837 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.6±0.1 g/cm3
Exact Mass	761.261841
PSA	194.02000
LogP	3.10
Refractive Index	1.732
Storage Conditions	-20°C

Activity & Biological Data

Additional Information	[1]. Takahashi N, et al. Sequence-dependent synergistic cytotoxicity of ecteinascidin-743 and paclitaxel in human breast cancer cell linesin vitro and in vivo. Cancer Res. 2002 Dec 1;62(23):6909-15. [2]. Atmaca H, et al. A diverse induction of apoptosis by trabectedin in MCF-7 (HER2-/ER+) and MDA-MB-453 (HER2+/ER-) breast cancer cells. Toxicol Lett. 2013 Jun 20;221(2):128-136. [3]. Germano G, et al. Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res. 2010 Mar 15;70(6):2235-44. [4]. Sessa C, et al. Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours. Eur J Cancer. 2009 Aug;45(12):2116-22.

Additional Information

[1]. Takahashi N, et al. Sequence-dependent synergistic cytotoxicity of ecteinascidin-743 and paclitaxel in human breast cancer cell linesin vitro and in vivo. Cancer Res. 2002 Dec 1;62(23):6909-15. [2]. Atmaca H, et al. A diverse induction of apoptosis by trabectedin in MCF-7 (HER2-/ER+) and MDA-MB-453 (HER2+/ER-) breast cancer cells. Toxicol Lett. 2013 Jun 20;221(2):128-136. [3]. Germano G, et al. Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res. 2010 Mar 15;70(6):2235-44. [4]. Sessa C, et al. Phase I clinical and pharmacokinetic study of trabectedin and cisplatin in solid tumours. Eur J Cancer. 2009 Aug;45(12):2116-22.

Frequently Asked Questions

What is the CAS number of Trabectedin?

The CAS number of Trabectedin is 114899-77-3.

What are the molecular formula and molecular weight of Trabectedin?

Trabectedin has molecular formula C39H43N3O11S and molecular weight 761.837 g/mol.

What are the upstream and downstream products of Trabectedin?

For Trabectedin, Upstream Products: Sesamol, 3-Methylcatechol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Trabectedin (CAS 114899-77-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1960074-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.