Ticagrelor

Also known as: AZD6140, Brilinta, Brilique, Possia, (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol

Ticagrelor (CAS 274693-27-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C23H28F2N6O4S and a molecular weight of 522.568 g/mol. Key properties include a boiling point of 777.6±70.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 424.0±35.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 274693-27-5
Jingsj CID: J-1960035-2
Molecular Formula: C₂₃H₂₈F₂N₆O₄S
Molecular Weight: 522.568 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	777.6±70.0 °C at 760 mmHg
Density	1.7±0.1 g/cm3
Flash Point	424.0±35.7 °C
Exact Mass	522.186096
PSA	163.74000
LogP	1.90
Vapor Pressure	0.0±2.8 mmHg at 25°C
Refractive Index	1.744

Activity & Biological Data

Additional Information	[1]. Aungraheeta R, et al. Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor. Blood. 2016 Dec 8;128(23):2717-2728. [2]. Gebremeskel S, et al. The reversible P2Y12 inhibitor ticagrelor inhibits metastasis and improves survival in mouse models of cancer. Int J Cancer. 2015 Jan 1;136(1):234-40. [3]. Sugidachi A, et al. A comparison of the pharmacological profiles of prasugrel and ticagrelor assessed by platelet aggregation, thrombus formation and haemostasis in rats. Br J Pharmacol. 2013 May;169(1):82-9.

Additional Information

[1]. Aungraheeta R, et al. Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor. Blood. 2016 Dec 8;128(23):2717-2728. [2]. Gebremeskel S, et al. The reversible P2Y12 inhibitor ticagrelor inhibits metastasis and improves survival in mouse models of cancer. Int J Cancer. 2015 Jan 1;136(1):234-40. [3]. Sugidachi A, et al. A comparison of the pharmacological profiles of prasugrel and ticagrelor assessed by platelet aggregation, thrombus formation and haemostasis in rats. Br J Pharmacol. 2013 May;169(1):82-9.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Ticagrelor?

The CAS number of Ticagrelor is 274693-27-5.

What are the molecular formula and molecular weight of Ticagrelor?

Ticagrelor has molecular formula C23H28F2N6O4S and molecular weight 522.568 g/mol.

What are the upstream and downstream products of Ticagrelor?

For Ticagrelor, Upstream Products: Isopropylidene Ticagrelor.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ticagrelor (CAS 274693-27-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1960035-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.