5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide

Also known as: A-803467, A803467, 5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide, 2-Furancarboxamide, 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)-, 5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5-dimethoxyphenylamide

5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide (CAS 944261-79-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C19H16ClNO4 and a molecular weight of 357.788 g/mol. Key properties include a melting point of 128-130?C, a boiling point of 450.6±45.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 226.3±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 944261-79-4
Jingsj CID: J-1959999-6
Molecular Formula: C₁₉H₁₆ClNO₄
Molecular Weight: 357.788 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	128-130?C
Boiling Point	450.6±45.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	226.3±28.7 °C
Exact Mass	357.076782
PSA	60.70000
LogP	4.93
Appearance	white to tan
Vapor Pressure	0.0±1.1 mmHg at 25°C
Refractive Index	1.611
Storage Conditions	Store at +4°C
Additional Property	DMSO: >10mg/mL

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Additional Information	[1]. McGaraughty, et al. A selective NaV1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide)], attenuates spinal neuronal activity in neuropathic rats. Journal of Pharmacology and Experimental Therapeutics (2008), [2]. Jarvis MF, et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8520-5. [3]. Joshi SK, et al. Additive antinociceptive effects of the selective Nav1.8 blocker A-803467 and selective TRPV1 antagonists in rat inflammatory and neuropathic pain models. http://www.ncbi.nlm.nih.gov/pubmed/19070548 [4]. Kort ME, et al. Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6812-5.

Additional Information

[1]. McGaraughty, et al. A selective NaV1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide)], attenuates spinal neuronal activity in neuropathic rats. Journal of Pharmacology and Experimental Therapeutics (2008), [2]. Jarvis MF, et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8520-5. [3]. Joshi SK, et al. Additive antinociceptive effects of the selective Nav1.8 blocker A-803467 and selective TRPV1 antagonists in rat inflammatory and neuropathic pain models. http://www.ncbi.nlm.nih.gov/pubmed/19070548 [4]. Kort ME, et al. Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6812-5.

Customs & Trade Information

HS Code	2932190090
Summary	2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide?

The CAS number of 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide is 944261-79-4.

What are the molecular formula and molecular weight of 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide?

5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide has molecular formula C19H16ClNO4 and molecular weight 357.788 g/mol.

Is 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide hazardous?

5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide?

For 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide, Upstream Products: 3,5-Dimethoxyaniline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide (CAS 944261-79-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959999-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.