Sulprostone

Also known as: Nalador, SHB 286, ZK-57671, CP-34089, (5Z)-7-{(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]-5-oxocyclopentyl}-N-(methylsulfonyl)-5-heptenamide, (5Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl}-N-(methylsulfonyl)hept-5-enamide, Sulprostonum, Sulprostona, EINECS 262-173-0

Sulprostone (CAS 60325-46-4) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C23H31NO7S and a molecular weight of 465.560 g/mol. Key properties include a melting point of 78.5-80ºC and a density of 1.3±0.1 g/cm3. It is classified under GHS with signal word Danger and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 60325-46-4
Jingsj CID: J-1959935-0
Molecular Formula: C₂₃H₃₁NO₇S
Molecular Weight: 465.560 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	78.5-80ºC
Density	1.3±0.1 g/cm3
Exact Mass	465.182129
PSA	138.38000
LogP	0.26
Refractive Index	1.589
Storage Conditions	−20°C
Additional Property	DMSO: >5 mg/mL

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger

H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation
H360 — May damage fertility or the unborn child

Activity & Biological Data

Target	EP3 Receptor
Additional Information	[1]. S Narumiya, et al. Prostanoid receptors: structures, properties, and functions. Physiol Rev. 1999 Oct;79(4):1193-226. [2]. Jenny Bulgarelli, et al. Skewing effect of sulprostone on dendritic cell maturation compared with dinoprostone. Cytotherapy. 2018 Jun;20(6):851-860. [3]. Yifan Shi, et al. Bioanalysis of sulprostone, a prostaglandin E 2 analogue and selective EP 3 agonist, in monkey plasma by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:51-57.

Target

EP3 Receptor

Additional Information

[1]. S Narumiya, et al. Prostanoid receptors: structures, properties, and functions. Physiol Rev. 1999 Oct;79(4):1193-226. [2]. Jenny Bulgarelli, et al. Skewing effect of sulprostone on dendritic cell maturation compared with dinoprostone. Cytotherapy. 2018 Jun;20(6):851-860. [3]. Yifan Shi, et al. Bioanalysis of sulprostone, a prostaglandin E 2 analogue and selective EP 3 agonist, in monkey plasma by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:51-57.

Frequently Asked Questions

What is the CAS number of Sulprostone?

The CAS number of Sulprostone is 60325-46-4.

What are the molecular formula and molecular weight of Sulprostone?

Sulprostone has molecular formula C23H31NO7S and molecular weight 465.560 g/mol.

Is Sulprostone hazardous?

Sulprostone has GHS signal word Danger and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Sulprostone?

For Sulprostone, Upstream Products: 7α-hydroxy-6β-(3'-hydroxy-4'-phenoxy-1'E-butenyl)-2-oxabicyclo[3.3.0]octan-3-one, (-)-Corey lactone diol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Sulprostone (CAS 60325-46-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959935-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.