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Pimozide

Also known as: 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone, 1-[4,4-Di-(4-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine, Orap, Opiran, R6238, McN-JR-6238, Neoperidole, Pimozidum, 双氟苯丁哌啶苯并咪唑酮, 1-{1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one, 1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinon, 3-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidyl)-1H-benzimidazol-2-one, 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one

Pimozide (CAS 2062-78-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C28H29F2N3O and a molecular weight of 461.546 g/mol. Key properties include a boiling point of 649.0±65.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 346.3±34.3 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
2062-78-4
Jingsj CID
J-1959895-9
Molecular Formula
C28H29F2N3O
Molecular Weight
461.546 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point649.0±65.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point346.3±34.3 °C
Exact Mass461.227875
PSA41.03000
LogP6.06
Vapor Pressure0.0±2.0 mmHg at 25°C
Refractive Index1.623
Additional PropertyDMSO: 18 mg/mL

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

TargetDopamine D2 receptor:1.4 nM (Ki) Dopamine D3 receptor:2.5 nM (Ki) Dopamine D1 receptor:588 nM (Ki) α1-adrenoceptor:39 nM (Ki) STAT3 STAT5
Additional Information[1]. Ybema CE, et al. Adrenoceptors and dopamine receptors are not involved in the discriminative stimulus effect of the 5-HT1A receptor agonist flesinoxan. Eur J Pharmacol. 1994 Apr 21;256(2):141-7. [2]. Cai N, et al. The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression. Am J Transl Res. 2017 Aug 15;9(8):3853-3866. eCollection 2017. [3]. Erik A. Nelson, et al. The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors. Blood. 2011 Mar 24; 117(12): 3421-3429.

Customs & Trade Information

HS Code2933990090
Summary2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Pimozide?

The CAS number of Pimozide is 2062-78-4.

What are the molecular formula and molecular weight of Pimozide?

Pimozide has molecular formula C28H29F2N3O and molecular weight 461.546 g/mol.

Is Pimozide hazardous?

Pimozide has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Pimozide?

For Pimozide, Upstream Products: 1-(Piperidin-4-yl)-1,3-dihydro-2H-benzimidazol-2-one, 1,1'-(4-chlorobutylidene)bis[4-fluorobenzene].

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Pimozide (CAS 2062-78-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959895-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.