Endomorphin-2

Also known as: Endomorphin 2, Endomorphin-2 (human, bovine), H-Tyr-Pro-Phe-Phe-NH2, Tyr-Pro-Phe-Phe-NH2, YPFF-NH2, L-Tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide, Tetrapeptide-15, MFCD01321064

Endomorphin-2 (CAS 141801-26-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C32H37N5O5 and a molecular weight of 571.66700 g/mol. Key properties include a melting point of 130-131℃, a boiling point of 972.4ºC at 760mmHg, a density of 1.292g/cm3 and a flash point of 541.9ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 141801-26-5
Jingsj CID: J-1959892-6
Molecular Formula: C₃₂H₃₇N₅O₅
Molecular Weight: 571.66700 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	130-131℃
Boiling Point	972.4ºC at 760mmHg
Density	1.292g/cm3
Flash Point	541.9ºC
Exact Mass	571.27900
PSA	167.85000
LogP	3.31360
Vapor Pressure	0mmHg at 25°C
Refractive Index	1.632
Storage Conditions	−20°C

Activity & Biological Data

Target	Ki: 20-30 nM (kappa3 opioid receptor)[1]
Additional Information	[1]. Goldberg IE, et al. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J Pharmacol Exp Ther. 1998 Aug;286(2):1007-13.

Frequently Asked Questions

What is the CAS number of Endomorphin-2?

The CAS number of Endomorphin-2 is 141801-26-5.

What are the molecular formula and molecular weight of Endomorphin-2?

Endomorphin-2 has molecular formula C32H37N5O5 and molecular weight 571.66700 g/mol.

What are the upstream and downstream products of Endomorphin-2?

For Endomorphin-2, Upstream Products: N-(tert-Butoxycarbonyl)-L-phenylalanine, L-Phenylalaninamide hydrochloride, Boc-L-Proline.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Endomorphin-2 (CAS 141801-26-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959892-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.