Afatinib

阿法替尼

Also known as: BIBW 2992, BIBW2992, Gilotrif, Tovok, (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl}-4-(dimethylamino)-2-butenamide, (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide, 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-

Afatinib (CAS 439081-18-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C24H25ClFN5O3 and a molecular weight of 485.94 g/mol. It is also known as BIBW 2992, BIBW2992 and Gilotrif. Key properties include a melting point of 100 - 102 °C, a boiling point of 676.9±55.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 363.2±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
439081-18-2
Jingsj CID
J-1959838-3
Molecular Formula
C24H25ClFN5O3
Chinese Name
阿法替尼
Molecular Weight
485.94 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point100 - 102 °C
Boiling Point676.9±55.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point363.2±31.5 °C

Frequently Asked Questions

What is the CAS number of Afatinib?

The CAS number of Afatinib is 439081-18-2.

What are the molecular formula and molecular weight of Afatinib?

Afatinib has molecular formula C24H25ClFN5O3 and molecular weight 485.94 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Afatinib (CAS 439081-18-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959838-3 (accessed 2026-10-25).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.